Preparation of aluminosilicate ferrierite (FER) zeolite nanosheets with controllable thickness in the presence of a sole organic ammonium is attractive, but still challenging. In this report, with the employment of N,N-diethyl-cis-2,6-dimethylpiperidinium (DMP) as both a structure directing agent and crystal growth inhibitor, aluminosilicate FER zeolite nanosheets, with a variety of crystal thicknesses, ranging from 6 to 200 nm, are successfully synthesized under hydrothermal conditions. Very interestingly, the amount of DMP in the starting gel is the key factor for crystal thickness control of aluminosilicate FER zeolite nanosheets. The obtained FER products, with different thicknesses, are well characterized by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), N2 sorption, thermogravimetric analysis (TG), inductively coupled plasma (ICP), and magic angle spinning nuclear magnetic resonance (MAS NMR) techniques. This simple strategy might provide a novel avenue for the synthesis of other zeolite nanosheets with controllable thickness.

Organic fluorines usually cannot act as halogen bond donors, as a result of the extreme electronegativity and least polarizability of the fluorine atom. However, when the electronegative ability of the substituents bound to the carbon atom is very strong, organic fluorines do show positive electrostatic potentials (ESPs) along the CF bond and thus can form halogen bonds with electron donors. In this work, the effects of six different substituents, i.e., NO2, CF3, CN, COOH, CHO, and CCH, on the ESPs of the F atom were studied using the M06‐2x method. When two or three substituents with very strong electron‐withdrawing ability, such as NO2 and CN, are linked to the C atom, positive ESPs take place on the outermost portion of the F atom. However, the ESPs remain negative along the CF bond with the introduction of relatively weak electron‐withdrawing substituents, irrespective of the number of the subsituents. In addition, some complexes between fluorinated molecules with positive ESPs on the F atom and NH3 were calculated, to characterize the structural and energetic features of these specific halogen bonds. Finally, some crystal structures extracted from the Cambridge Structural Database were selected to provide experimental evidence of these interactions involving the CF bond. The results presented in this work are very important for the modern definition of halogen bonding as well as for the development of pharmaceuticals and a wide range of functional material. © 2015 Wiley Periodicals, Inc.

Novel magnetically recyclable Fe3O4@Pd nanoparticles (NPs) were favorably synthesized by fixing palladium on the surface of nitrogen-doped magnetic nanocomposites. These catalysts were fully characterized by Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), transmission electron microscopy (TEM), thermogravimetric analysis (TG), and X-ray photoelectron spectroscopy (XPS). The prepared catalyst exhibited good catalytic activity for Suzuki–Miyaura coupling reactions of aryl or heteroaryl halides (I, Br, Cl) with arylboronic acids. These as-prepared catalysts could be readily isolated from the reaction liquid by an external magnet and reused at least ten times with excellent yields achieved. In addition, using this protocol, the marketed drug crizotinib (anti-tumor) could be easily synthesized.

Research on the synthesis and biological activity of heterocyclic compounds is an important developmental oriental in pesticide and medicine chemistry 1. It is well known that nicotinic acid and their derivatives exhibit excellent biological activity. Novel pyridine and related derivatives 2 are attractive molecules because their structure is present in several natural compounds, drugs or argochemicals. Additionally, various types of acyl-thiourea derivatives had comprehensive bioactivities, due to they held amide group 3 and thioamide group. Microwave technique, meanwhile, has been widely used for a variety of organic reactions, such as Claisen, heterocyclic synthesis, oxidation, hydrolysis, esterification, etherification and so on. Many reports 4 have been published in favour of its considerable accelerations of the reaction rates and satisfactory yields. In order to search for new compounds with good biological activity, ten thiourea derivatives (3a-j) were synthesized under microwave irradiation. Their structures are confirmed by 1 H NMR, IR, MS and elemental analysis. The preliminary biological tests show that these compounds had moderate fungicidal activity. EXPERIMENTAL Nicotinic acid, substituted aniline were commercially available. Melting points were determined using a X-4 melting apparatus and were uncorrected. Infrared spectra were recorded on a Bruker Equinox55 spectrophotometer as potassium

No abstract