The aim of this study was to analyze the prevalence of mild cognitive impairment (MCI) among the aging population (60 years of age and above) in China. Epidemiological investigations on MCI in online Chinese journals were identified manually using the CQVIP, CNKI, and Wanfang databases. Articles from journals published in English were identified using PubMed and Web of Science. Original studies that included prevalence surveys of MCI were selected. Forty-eight relevant studies were included in the analysis, covering 22 provinces in China. Our results showed that the pooled prevalence of MCI in the older Chinese population was 14.71% (95% confidence interval [CI], 14.50-14.92%). The prevalence was 16.72% (95% CI, 15.68-17.71%) in clinical samples vs. 14.61% (95% CI, 14.40-14.83%) in nonclinical samples (χ2=16.60, P<0.01), and 15.20% (95% CI, 14.91-15.49%) in screened samples vs. 14.16% (95% CI, 13.85-14.46%) in diagnosed samples (χ2=22.11, P<0.01). People of older age, of female sex, or living in rural areas or western China were associated with a higher prevalence of MCI. The prevalence of MCI was high in Chinese older adults, and even higher in those who were older, female, or living in rural areas or western China. Future studies are recommended to address the prevalence of MCI in the other 12 provinces of China. Furthermore, diagnostic assessments should be included in the identification of MCI.
The REFINE SPECT registry will provide a resource for collaborative projects related to the latest generation SPECT-MPI. It will aid in the development of new artificial intelligence tools for automated diagnosis and prediction of prognostic outcomes.
OBJECTIVES-We aimed to study the ability of automated myocardial perfusion imaging analysis in comparison to visual analysis in major adverse cardiac events (MACE) prediction. BACKGROUND-Quantitative analysis has not been compared to clinical visual analysis in prognostic studies. METHODS-From the multi-center REgistry of Fast Myocardial Perfusion Imaging with NExt generation SPECT (REFINE SPECT), 19,495 patients (64±12 years, 56% male) undergoing stress Tc-99m SPECT-MPI were followed for 4.5±1.7 years for MACE. Perfusion abnormalities were assessed visually and categorized as normal, probably normal, equivocal, and abnormal. Stress total perfusion deficit (TPD), quantified automatically was categorized as TPD=0%,
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