, this report was posted as an MMWR Early Release on the MMWR website (https://www.cdc.gov/mmwr). Globally, approximately 170,000 confirmed cases of coronavirus disease 2019 (COVID-19) caused by the 2019 novel coronavirus (SARS-CoV-2) have been reported, including an estimated 7,000 deaths in approximately 150 countries (1). On March 11, 2020, the World Health Organization declared the COVID-19 outbreak a pandemic (2). Data from China have indicated that older adults, particularly those with serious underlying health conditions, are at higher risk for severe COVID-19-associated illness and death than are younger persons (3). Although the majority of reported COVID-19 cases in China were mild (81%), approximately 80% of deaths occurred among adults aged ≥60 years; only one (0.1%) death occurred in a person aged ≤19 years (3). In this report, COVID-19 cases in the United States that occurred during February 12-March 16, 2020 and severity of disease (hospitalization, admission to intensive care unit [ICU], and death) were analyzed by age group. As of March 16, a total of 4,226 COVID-19 cases in the United States had been reported to CDC, with multiple cases reported among older adults living in long-term care facilities (4). Overall, 31% of cases, 45% of hospitalizations, 53% of ICU admissions, and 80% of deaths associated with COVID-19 were among adults aged ≥65 years with the highest percentage of severe outcomes among persons aged ≥85 years. In contrast, no ICU admissions or deaths were reported among persons aged ≤19 years. Similar to reports from other countries, this finding suggests that the risk for serious disease and death from COVID-19 is higher in older age groups. Data from cases reported from 49 states, the District of Columbia, and three U.S. territories (5) to CDC during February 12-March 16 were analyzed. Cases among persons repatriated to the United States from Wuhan, China and from Japan (including patients repatriated from cruise ships) were excluded. States and jurisdictions voluntarily reported data on laboratory-confirmed cases of COVID-19 using previously developed data collection forms (6). The cases described in this report include both COVID-19 cases confirmed by state or local public health laboratories as well as those with a positive test at the state or local public health laboratories and confirmation at CDC. No data on serious underlying health conditions were available. Data on these cases are preliminary and are missing for some key characteristics of CDC COVID-19 Response Team

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Local areas that received Federal Section 317 immunization funds were sampled separately: Chicago, Illinois; New York, New York; Philadelphia County, Pennsylvania; Bexar County, Texas; and Houston, Texas. Two local areas (in Texas) were oversampled: El Paso County and Hidalgo County. Three territories was sampled separately in 2015: Guam, Puerto Rico, and the U.S. Virgin Islands. ¶ All identified cellular telephone households were eligible for interview. Sampling weights were adjusted for dual-frame (landline and cellular telephone), nonresponse, noncoverage, and overlapping samples of mixed telephone users. A description of NIS-Teen dual-frame survey methodology and its effect on reported vaccination estimates is available at http://www.cdc. gov/vaccines/imz-managers/coverage/nis/child/dual-frame-sampling.html. ** The overall Council of American Survey Research Organizations (CASRO) response rate was 33.0%. Response rates for the landline and cell phone samples were 56.4% and 29.8%, respectively. For completed interviews in the states and local areas, 4,784 landline calls (53.4%) and 17,091 cell phone calls (48.9%) had adequate provider data. Overall, for states and local areas, 22% of completed interviews with adequate provider data were from landlines and 78% were from cell phones. For U.S. territories, the landline and cell phone sample CASRO rates were 52.1% and 22.6% for Guam, 57.8% and 37.4% for Puerto Rico, and 69.6% and 41.5% for the U.S. Virgin Islands, respectively. The CASRO response rate is the product of three other rates: 1) the resolution rate (the proportion of telephone numbers that can be identified as either for business or residence), 2) the screening rate (the proportion of qualified households that complete the screening process), and 3) the cooperation rate (the proportion of contacted eligible households for which a completed interview is obtained National Vaccination CoverageIn 2015, among males, coverage with ≥1 HPV vaccine dose was 49.8% and with ≥3 doses was 28.1%; among females coverage with ≥1 dose was 62.8% and with ≥3 doses was 41.9% (Table 1) (Figure 1) Vaccination Coverage by Selected CharacteristicsIn 2015, ≥1-dose HPV vaccination coverage among females aged 13 years was lower than coverage among females aged ≥15 years, but was similar among males in all age groups (Table 1). Although HPV vaccination coverage remained higher among females than among males, the percentage point difference in coverage estimates decreased over time (Figure 1). Coverage with each HPV vaccine dose and with ≥1 MenACWY dose was higher among Hispanic adolescents than among non-Hispanic white (white) adolescents; however, coverage with ≥2 measles, mumps, and rubella vaccine (MMR) doses and ≥3 hepatitis B vaccine doses was lower among Hispanic adolescents (Table 2). Coverage with ≥1 HPV vaccine dose was higher among non-Hispanic black (black) adolescents, compared with white adolescents. Adolescents living below the federal poverty level had higher ≥1-and ≥2-dose HPV vaccination coverage than did a...

Before the introduction of the quadrivalent meningococcal conjugate vaccine, the incidence of meningococcal disease in the United States decreased to a historic low. However, meningococcal disease still causes a substantial burden of disease among all age groups. Future vaccination strategies may include targeting infants and preventing serogroup B meningococcal disease.