CT virtual colonoscopy with the use of a three-dimensional approach is an accurate screening method for the detection of colorectal neoplasia in asymptomatic average-risk adults and compares favorably with optical colonoscopy in terms of the detection of clinically relevant lesions.
Computed tomographic (CT) colonography continues to evolve rapidly. Advances in scanning and display technologies, encouraging performance data, and increased utilization necessitate clarification and standardization of results reporting in CT colonography. There are several reasons for this. First and most important, standardized reporting can better assist patients and referring physi-cians in making management decisions on the basis of the results of CT colonography. The precedent of the mammography Breast Imaging Reporting and Data System, or BI-RADS, schema is a strong incentive to provide a similar structure for CT colonography. Second, as more examinations are performed, the likelihood increases that radiologists interpreting results of a CT colonography examination performed at one center will require comparison to examination results and reports generated at other sites. As has been seen with mammography, a common set of terms facilitates this kind of assessment (1). Third, as utilization of CT colonography increases, our colleagues in other medical specialties, the various third-party payers, and the general public will insist on larger-scale evaluations of examination performance, examination quality, patient outcome, and cost. Here again, a common approach to interpretation will assist us in meeting these demands. Finally, a common scheme for reporting facilitates structured reporting.The purpose of this communication is to facilitate clear and consistent communication of CT colonography results. The authors-an ad hoc group of investigators active in the area of CT colonogra-
Background Psychiatric sequelae of exposure to parental verbal abuse (PVA) appears to be comparable to that of non-familial sexual abuse and witnessing domestic violence. Diffusion Tensor Imaging (DTI) was used to ascertain whether PVA was associated with abnormalities in brain white matter (WM) tract integrity. Method 1271 healthy young adults were screened for exposure to childhood adversity. DTI was collected on 16 unmedicated subjects with history of high-level exposure to PVA but no other form of maltreatment (4M/12F, mean age 21.9±2.4 yrs), and 16 healthy controls (5M/11F, 21.0±1.6 yrs). Group differences in fractional anisotropy (FA), covaried by parental education and income, were assessed using Tract-Based Spatial Statistics (TBSS), and correlated with symptom ratings and verbal IQ. Results Three WM tract regions had significantly reduced FA: (1) arcuate fasciculus in left superior temporal gyrus, (2) cingulum bundle by the posterior tail of the left hippocampus, and (3) the left body of the fornix. FA in these areas were strongly associated with average PVA scores (rs=-0.701, P<0.001; rs=-0.801, P<0.001; rs=0.524, P=0.002, respectively), and levels of maternal verbal abuse. Across groups FA in region 1 correlated with verbal IQ (rs=0.411, P=0.024) and verbal comprehension index (rs=0.437, P=0.016). FA in region 2 was inversely associated with ratings of depression (rs=-0.504), dissociation (rs=-0.373) and ‘limbic irritability’ (rs= -0.602). FA in region 3 was inversely correlated with ratings of somatization (rs=-0.389) and anxiety (rs=-0.311). Conclusions Exposure to PVA may be associated with alteration in the integrity of neural pathways with implications for language development and psychopathology.
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