Dear Editor, Chronic sarcoidosis is a rare granulomatous multisystem disease and may be life threatening when lung-involvement is present. Cutaneous sarcoidosis (CS) manifests in up to 35% of the cases and may be an apparent indicator to early diagnosis. 1,2 It is crucial to distinguish between unspecific CS lesions, related to granulomatous inflammation, and specific ones, related to granuloma infiltration of the skin. 1 Usually,
Objectives: Basal cell carcinoma (BCC) is the most common skin tumor with an annually increasing incidence. Standard care requires several visits for diagnosis and treatment. Optical coherence tomography (OCT) as a diagnostic tool increases the sensitivity (95%) and specificity (77%) of the diagnosis of BCC. Although laser therapy is not the standard of care, the long-pulsed 1064 nm Nd:YAG laser seems to be a promising option. However, data are scarce. The published papers had a short follow-up (FU) time and used to some extent inferior methods to detect complete tumor clearance. To address this research gap, this study evaluates the efficiency of laser treatment by FU OCT. We pursue a patient-focused approach and combine OCT with Nd:YAG laser treatment in one procedure. Materials and Methods: The study was conducted as a prospective, single-center trial that recruited biopsy-confirmed or OCT-proven BCC with a tumor thickness of less than 1.2 mm. Patients underwent two or three repeated sessions with the Nd:YAG laser (5-6 mm spot, fluence of 120-140 J/cm 2 , pulse duration of 8-10 milliseconds). Each BCC was assessed at baseline, and 3 and 12 months after laser treatment by clinical image, dermoscopy, and OCT. Incomplete tumor clearance (ITC) was defined as a clearly detectable BCC on the OCT image or a biopsy-confirmed BCC in the treated area. Results: Forty-five patients completed the 12-month FU (46.7% women; median age of 74.0 [52-88] years) with a total number of 78 BCC lesions. At baseline, all patients had their BCC diagnosed by OCT (tumor thickness of 0.6 [0.4; 0.8] mm), 15.4% lesions were additionally diagnosed by histopathology. The most common subtype of BCC was superficial (48.7%), followed by nodular (47.4%) and infiltrative (3.8%). ITC rate after the treatment using Nd:YAG laser was 30.8% (95% CI: 20.8%-42.2%) (24/78) after 3 months and 7.4% (95% CI: 2.1%-17.9%) (4/54) after 12 months. ITC was not associated with histological subtype, tumor thickness, or location. If ITC was detected, the lesion was treated again. Out of 19 lesions with at least one additional laser treatment, 7 lesions (36.8%) suffered from incomplete tumor removal. In 46.7% of the treated lesions, the cosmetic outcome was rated as moderate or severe scarring after 12 months. Conclusion: Our results demonstrate that the ITC rate of BCC treated with the Nd:YAG laser is much higher (up to one-third) than reported, although the laser settings were identical to prior studies. This is especially evident at the 3-month
SummaryBackground and objectivesTo date, there is no structured program for dermatoscopy training during residency in Germany. Whether and how much dermatoscopy training is acquired is left to the initiative of each resident, although dermatoscopy is one of the core competencies of dermatological training and daily practice. The aim of the study was to establish a structured dermatoscopy curriculum during residency at the University Hospital Augsburg.Patients and methodsAn online platform with dermatoscopy modules was created, accessible regardless of time and place. Practical skills were acquired under the personal guidance of a dermatoscopy expert. Participants were tested on their level of knowledge before and after completing the modules. Test scores on management decisions and correct dermatoscopic diagnosis were analyzed.ResultsResults of 28 participants showed improvements in management decisions from pre‐ to posttest (74.0% vs. 89.4%) and in dermatoscopic accuracy (65.0% vs. 85.6%). Pre‐ vs. posttest differences in test score (7.05/10 vs. 8.94/10 points) and correct diagnosis were significant (p < 0.001).ConclusionsThe dermatoscopy curriculum increases the number of correct management decisions and dermatoscopy diagnoses. This will result in more skin cancers being detected, and fewer benign lesions being excised. The curriculum can be offered to other dermatology training centers and medical professionals.
ZusammenfassungHintergrund und ZieleBislang gibt es in Deutschland kein strukturiertes Programm für die Dermatoskopieausbildung während der Facharztausbildung. Es bleibt der Initiative des einzelnen Assistenzarztes überlassen, ob und in welchem Umfang er sich in der Dermatoskopie weiterbildet, obwohl die Dermatoskopie zu den Kernkompetenzen der dermatologischen Ausbildung und der täglichen Praxis gehört. Ziel der Studie war die Etablierung eines strukturierten Dermatoskopie‐Curriculums während der dermatologischen Facharztausbildung am Universitätsklinikum Augsburg.Patienten und MethodikEs wurde eine Online‐Plattform mit Dermatoskopie‐Modulen geschaffen, auf die von überall und jederzeit zugegriffen werden kann. Praktische Fertigkeiten wurden unter individueller Anleitung eines Dermatoskopie‐Experten erworben. Die Teilnehmer wurden vor und nach Abschluss der Module auf ihren Wissensstand getestet. Die Testergebnisse zum therapeutischen Management und zur korrekten dermatoskopischen Diagnose wurden analysiert.ErgebnisseDie Ergebnisse der 28 Teilnehmer verbesserten sich vom Eingangs‐ zum Abschlusstest bei der Managemententscheidung (74,0% vs. 89,4%) und bei der dermatoskopischen Genauigkeit (65,0% vs. 85,6%). Die Unterschiede zwischen Eingangs‐ und Abschlusstest bei der Gesamtpunktzahl (7,05/10 vs. 8,94/10 Punkte) und bei der richtigen Diagnose waren signifikant (p < 0,001).SchlussfolgerungenDas Dermatoskopie‐Curriculum verbessert die Managemententscheidungen und die dermatoskopische Diagnostik der Teilnehmer. Das wird dazu führen, dass mehr Hautkrebsfälle erkannt werden und weniger gutartige Läsionen reseziert werden müssen. Das Curriculum kann anderen dermatologischen Ausbildungszentren und Gesundheitsberufen angeboten werden.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.