Background
Radial artery occlusion is a known complication following transradial cardiac catheterization. A shorter duration of postprocedural radial clamp time may reduce radial artery occlusion (
RAO
) but might be associated with incomplete hemostasis.
Methods and Results
In total, 568 patients undergoing transradial diagnostic cardiac catheterization were randomly assigned to either 20 minutes (ultrashort) or 60 minutes (short) hemostatic compression time using patent hemostasis. Subsequently, clamp pressure was reduced gradually over 20 minutes. Access site hemostasis and
RAO
were assessed after clamp removal. Repeated assessment of
RAO
was determined at 1 week in 210 (37%) patients. Mean age was 64±11 years, and 30% were female. Percutaneous coronary intervention was performed in 161 patients.
RAO
immediately after clamp removal was documented in 14 (4.9%) and 8 (2.8%) patients in the 20‐ and 60‐minute clamp application groups, respectively (
P
=0.19). The incidence of grade 1 hematoma was higher in the 20‐minute group (6.7% versus 2.5%,
P
=0.015).
RAO
at 1 week after the procedure was 2.9% and 0.9% in the 20‐ and 60‐minute groups, respectively (
P
=0.36). Requirement for clamp retightening (36% versus 16%,
P
=0.01) was higher among patients who had
RAO
. Need for clamp retightening was the only independent predictor of
RAO
(
P
=0.04).
Conclusions
Ultrashort radial clamp application of 20 minutes is not preferable to a short duration of 60 minutes. The 60‐minute clamp duration is safe and provides good access site hemostasis with low
RAO
rates.
Clinical Trial Registration
URL
:
http://www.clinicaltrials.gov
. Unique identifier:
NCT
02269722.
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