We present an all-fiber supercontinuum source based on a passively mode-locked erbium fiber laser and a small-effective-area, germanium-doped silica fiber. The parallels between this system and the continuum generated in microstructured fibers with 800-nm pulses are discussed, and the role of dispersion is investigated experimentally. We construct a hybrid fiber by fusion splicing lengths of different-dispersion fiber together, generating more than an octave of bandwidth.
We demonstrate a Raman fiber laser with an operating wavelength of 1480 nm and record output power of 81 W. High-power operation is enabled by a long-period grating used to frustrate backward lasing at the Stokes wavelength in the Yb-doped fiber amplifier. A cascaded Raman fiber with a long-wavelength fundamental mode cutoff enables efficient multiple Stokes scattering from 1117 to 1480 nm while preventing further unwanted scattering to 1590 nm.
The role of G proteins in mediating the responses of the heart to circulating catecholamines and to the influences of the autonomic nervous system is of special interest to cardiologists. It is evident that G proteins are essential links in the cascade of biochemical events that ensure when neurotransmitters and hormones interact with receptors on myocardial cells. It is likely [corrected] that dysfunction of G proteins plays a role in cardiovascular pathophysiology. With current methodologies, especially molecular biological and recombinant DNA techniques, and with transgenic animal models that can relate physiological function and specific gene dosage, some cardiovascular diseases may be traced to G protein-related defects.
Soil-disrupting activities within a school courtyard caused the largest outbreak to date of histoplasmosis among adolescents. Improved efforts are needed to educate the community in endemic areas about histoplasmosis to prevent the occurrence of such outbreaks in the future. In addition, increased awareness among health care providers of this disease would facilitate appropriate diagnosis and treatment.
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