A combination is presented of the inclusive deep inelastic cross sections measured by the H1 and ZEUS Collaborations in neutral and charged current unpolarised e ± p scattering at HERA during the period 1994-2000. The data span six orders of magnitude in negative four-momentum-transfer squared, Q 2 , and in Bjorken x. The combination method used takes the correlations of systematic uncertainties into account, resulting in an improved accuracy. The combined data are the sole input in a NLO QCD analysis which determines a new set of parton distributions, HERAPDF1.0, with small experimental uncertainties. This set includes an estimate of the model and parametrisation uncertainties of the fit result.
Measurements of open charm production cross sections in deep-inelastic ep scattering at HERA from the H1 and ZEUS Collaborations are combined. Reduced cross sections σ cc red for charm production are obtained in the kinematic range of photon virtuality 2.5 ≤ Q 2 ≤ 2000 GeV 2 and Bjorken scaling variable 3 · 10 −5 ≤ x ≤ 5 · 10 −2 . The combination method accounts for the correlations of the systematic uncertainties among the different data sets. The combined charm data together with the combined inclusive a e-mail: levy@alzt. deep-inelastic scattering cross sections from HERA are used as input for a detailed NLO QCD analysis to study the influence of different heavy flavour schemes on the parton distribution functions. The optimal values of the charm mass as a parameter in these different schemes are obtained. The implications on the NLO predictions for W ± and Z production cross sections at the LHC are investigated. Using the fixed flavour number scheme, the running mass of the charm quark is determined.
Beauty production in deep inelastic scattering with events in which a muon and a jet are observed in the final state has been measured with the ZEUS detector at HERA using an integrated luminosity of 114 pb −1 . The fraction of events with beauty quarks in the data was determined using the distribution of the transverse momentum of the muon relative to the jet. The cross section for beauty production was measured in the kinematic range of photon virtuality, Q 2 > 2 GeV 2 , and inelasticity, 0.05 < y < 0.7, with the requirement of a muon and a jet. Total and differential cross sections are presented and compared to QCD predictions. The beauty contribution to the structure function F 2 was extracted and is compared to theoretical predictions.
The galactose specific lectin LecA mediates biofilm formation in the opportunistic pathogen P. aeruginosa . The interaction between LecA and aromatic β-galactoside biofilm inhibitors involves an intermolecular CH-π T-shape interaction between C(ε1)-H of residue His50 in LecA and the aromatic ring of the galactoside aglycone. The generality of this interaction was tested in a diverse family of β-galactosides. LecA binding to aromatic β-galactosides (KD ∼ 8 μM) was consistently stronger than to aliphatic β-galactosides (KD ∼ 36 μM). The CH-π interaction was observed in the X-ray crystal structures of six different LecA complexes, with shorter than the van der Waals distances indicating productive binding. Related XH/cation/π-π interactions involving other residues were identified in complexes of aromatic glycosides with a variety of carbohydrate binding proteins such as concanavalin A. Exploiting such interactions might be generally useful in drug design against these targets.
A gamma-ray spectroscopic measurement of the N = Z nucleus 68Se has been made following the 12C(58Ni,2n) reaction at 185 and 220 MeV using Gammasphere and the Argonne Fragment Mass Analyzer. Despite a very low production cross section of 200(50) &mgr;b, two distinct rotational bands were found; the ground state band consistent with oblate collective rotation, and an excited band consistent with prolate rotation. These observations support long-standing predictions that nuclear ground states with substantial oblate (beta(2) approximately -0.3) deformation should exist in this region.
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