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Background: In Nigeria, an infection caused by Schistosoma haematobium has been known to be endemic especially among residents along Rivers, and it is responsible for considerable public health problems. Aims: This study aimed at assessing the prevalence and intensity of infection among the vulnerable communities. Study Design: A cross-sectional study involving 1,404 participants within age bracket 5-55 years old and above, in ten communities across five Local Government Areas along River Benue in Adamawa State, was conducted. Urine samples were collected from randomly selected study subjects and were examined using centrifugation and sedimentation techniques. The intensity of infection was ascertained as eggs/10mls of urine and values expressed as Mean ± SD. Data on demography were obtained by structured questionnaires. The simple percentage was used and Chi-square as well to ascertain the associations between prevalence and other parameters. P<0.05 was considered as significant. Results and Discussion: The overall prevalence and intensity of infection were 23.2% and 513±0.05 eggs/10 ml of urine respectively. Kabawa had the highest infection rate and intensity with 12.4% and 80±0.02 respectively. The lowest was recorded in Kangle (12.3% and 24±0.82 eggs/10 ml), with a significant association between parasite intensity and community (p<0.05). Gender-related prevalence and intensity revealed that males (25.5% and 289±4.66 eggs/10 ml) were more affected than the females (20.8% and 206±4.49 eggs/10 ml). Participants within age bracket 5-14 years old had the highest prevalence (36.6%) and intensity (142±0.005 eggs/10 ml), while the lowest was recorded among age group 45-54 years old with 9.0% and 42±0.040 eggs/10 ml. Prevalence and intensity of infection was highest among Subjects fetching water from River/Streams (31.8%, 46±0.080 egg/10 ml of urine), whereas the least were observed among borehole fetchers (13.8% and 241±0.302 egg/10 ml of urine). Occupational related prevalence and intensity were highest among Fishers with 35.0% and 188±0.012 egg/10 ml of urine. Chemotherapy and Health Education should be advocated across the study area. Conclusion: This study has established that Schistosoma haematobium infection is prevalent among the residents living along the River Benue in Adamawa State, Nigeria. Although infection was more among the males than the females, there was no significant difference, but there were significant differences in prevalence and intensity with age, the source of drinking water, and occupation.

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Owing to the adverse effect of synthetic pesticides, there has been increasing need to search for natural and environment friendly pesticides of plant origin as agents for control of vector of mosquito-borne diseases. This study was aimed to investigate the larvicidal activities of North eastern botanicals against vector of mosquitoes-borne diseases. Five mosquito repellent plants used by the indigenous people of north eastern, Nigeria were analysed for their effectiveness against Anopheline mosquitoes. The methanol and petroleum ether were analysed for their phytochemical properties. The methanol and petroleum ether extracts were investigated for phytochemical compounds with larvicidal activities against anopheline 3rd instar larvae through using deferent extracts of methanol and petroleum ether of different concentration that ranged from 50-200 ppm.  The larvicidal were observed after every six hours for total period of 36 hours. The extracts of Hyptis suaveolens and Azadirachta indica of both methanol and petroleum ether extracts showed high toxicity effects against anopheline. The test plants contained phenol, alkaloids, flavonoids, tannins, azadrachtin, glycosides saponins, terpenoids and steroids. In conclusion, the present plant extracts have potentials for development of new and safe control products for mosquitoes. As natural occurring insecticides, these plants derived materials that could be useful as an alternative for synthetic insecticides.

This study was aimed to investigate the insecticidal activities of some selected ethnobotanicals against culicine mosquitoes. Various part of plant material collected were extracted using Soxhlet apparatus Methanol and Petroleum ether were used as solvents. Quantitative phytochemical Analysis for the crude extracts was carried out for the presence of azadrachtin, terpenoids, alkaloids, tannins, saponins, glycoside, steroids phenol and flavonoids. The larvicidal potentials of the various crude extracts were then tested against culicine mosquitoes. More yields of phytochemical constituents (80.78 mg) were found in total of 900 g used for methanol extracts as compared to 57.64 mg found in 900 g used in petroleum ether extracts. All the extracts of methanol and petroleum ether of the different plant used showed larvicidal potentials against culicine 3rd instar larvae. The LC50 of the methanol extracts (37.32, 38.52, 42.05, 45.91, 68.78, 126.56, and 141.73 ppm) of E. globulus, O. kilimanscharicum, H. suaveolens, Neem seeds, neem stem leave and orange peels respectively, are far better than their counterparts of petroleum ether extracts with LC50 (100.25, 115.53, 145.88, 68.44, 114.55, 46.79, and 175.07 ppm). The larvicidal effect of individual isolates of alkaloids, tannin, saponins, azadirachtin, phenol and steroids demonstrated larvicidal potentials against 3rd instar larvae of culicine, where, terpenoids, flavonoids and glycoside showed no larvicidal potentials against culicine larvae. The larvicidal potential of each plant depend on the number of active ingredients and quantity available in each extract. In conclusion, the present plant extracts have potentials for development of new and safe control products for culicine mosquitoes.