We developed a fast,
single-step sonochemical strategy for the
green manufacturing of magnetite (Fe
3
O
4
) magnetic
nanoparticles (MNPs), using iron sulfate (FeSO
4
) as the
sole source of iron and sodium hydroxide (Na(OH)) as the reducing
agent in an aqueous medium. The designed methodology reduces the environmental
impact of toxic chemical compounds and minimizes the infrastructure
requirements and reaction times down to minutes. The Na(OH) concentration
has been varied to optimize the final size and magnetic properties
of the MNPs and to minimize the amount of corrosive byproducts of
the reaction. The change in the starting FeSO
4
concentration
(from 5.4 to 43.1 mM) changed the particle sizes from (20 ± 3)
to (58 ± 8) nm. These magnetite MNPs are promising for biomedical
applications due to their negative surface charge, good heating properties
(≈324 ± 2 W/g), and low cytotoxic effects. These results
indicate the potential of this controlled, easy, and rapid ultrasonic
irradiation method to prepare nanomaterials with enhanced properties
and good potential for use as magnetic hyperthermia agents.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.