Health telematics is a growing up issue that is becoming a major improvement on patient lives, especially in elderly, disabled, and chronically ill. In recent years, information and communication technologies improvements, along with mobile Internet, offering anywhere and anytime connectivity, play a key role on modern healthcare solutions. In this context, mobile health (m-Health) delivers healthcare services, overcoming geographical, temporal, and even organizational barriers. M-Health solutions address emerging problems on health services, including, the increasing number of chronic diseases related to lifestyle, high costs of existing national health services, the need to empower patients and families to self-care and handle their own healthcare, and the need to provide direct access to health services, regardless of time and place. Then, this paper presents a comprehensive review of the state of the art on m-Health services and applications. It surveys the most significant research work and presents a deep analysis of the top and novel m-Health services and applications proposed by industry. A discussion considering the European Union and United States approaches addressing the m-Health paradigm and directives already published is also considered. Open and challenging issues on emerging m-Health solutions are proposed for further works.

BackgroundNew possibilities for mHealth have arisen by means of the latest advances in mobile communications and technologies. With more than 1 billion smartphones and 100 million tablets around the world, these devices can be a valuable tool in health care management. Every aid for health care is welcome and necessary as shown by the more than 50 million estimated deaths caused by illnesses or health conditions in 2008. Some of these conditions have additional importance depending on their prevalence.ObjectiveTo study the existing applications for mobile devices exclusively dedicated to the eight most prevalent health conditions by the latest update (2004) of the Global Burden of Disease (GBD) of the World Health Organization (WHO): iron-deficiency anemia, hearing loss, migraine, low vision, asthma, diabetes mellitus, osteoarthritis (OA), and unipolar depressive disorders.MethodsTwo reviews have been carried out. The first one is a review of mobile applications in published articles retrieved from the following systems: IEEE Xplore, Scopus, ScienceDirect, Web of Knowledge, and PubMed. The second review is carried out by searching the most important commercial app stores: Google play, iTunes, BlackBerry World, Windows Phone Apps+Games, and Nokia's Ovi store. Finally, two applications for each condition, one for each review, were selected for an in-depth analysis.ResultsSearch queries up to April 2013 located 247 papers and more than 3673 apps related to the most prevalent conditions. The conditions in descending order by the number of applications found in literature are diabetes, asthma, depression, hearing loss, low vision, OA, anemia, and migraine. However when ordered by the number of commercial apps found, the list is diabetes, depression, migraine, asthma, low vision, hearing loss, OA, and anemia. Excluding OA from the former list, the four most prevalent conditions have fewer apps and research than the final four. Several results are extracted from the in-depth analysis: most of the apps are designed for monitoring, assisting, or informing about the condition. Typically an Internet connection is not required, and most of the apps are aimed for the general public and for nonclinical use. The preferred type of data visualization is text followed by charts and pictures. Assistive and monitoring apps are shown to be frequently used, whereas informative and educational apps are only occasionally used.ConclusionsDistribution of work on mobile applications is not equal for the eight most prevalent conditions. Whereas some conditions such as diabetes and depression have an overwhelming number of apps and research, there is a lack of apps related to other conditions, such as anemia, hearing loss, or low vision, which must be filled.

There are few cost-utility and cost-effectiveness studies for e-health and m-health systems in the literature. Some cost-effectiveness studies demonstrate that telemedicine can reduce the costs, but not all. Among the main limitations of the economic evaluations of telemedicine systems are the lack of randomized control trials, small sample sizes, and the absence of quality data and appropriate measures.

In a world where the industry of mobile applications is continuously expanding and new health care apps and devices are created every day, it is important to take special care of the collection and treatment of users' personal health information. However, the appropriate methods to do this are not usually taken into account by apps designers and insecure applications are released. This paper presents a study of security and privacy in mHealth, focusing on three parts: a study of the existing laws regulating these aspects in the European Union and the United States, a review of the academic literature related to this topic, and a proposal of some recommendations for designers in order to create mobile health applications that satisfy the current security and privacy legislation. This paper will complement other standards and certifications about security and privacy and will suppose a quick guide for apps designers, developers and researchers.

Nowadays, coronavirus (COVID-19) is getting international attention due it considered as a life-threatened epidemic disease that hard to control the spread of infection around the world. Machine learning (ML) is one of intelligent technique that able to automatically predict the event with reasonable accuracy based on the experience and learning process. In the meantime, a rapid number of ML models have been proposed for predicate the cases of COVID-19. Thus, there is need for an evaluation and benchmarking of COVID-19 ML models which considered the main challenge of this study. Furthermore, there is no single study have addressed the problem of evaluation and benchmarking of COVID diagnosis models. However, this study proposed an intelligent methodology is to help the health organisations in the selection COVID-19 diagnosis system. The benchmarking and evaluation of diagnostic models for COVID-19 is not a trivial process. There are multiple criteria requires to evaluate and some of the criteria are conflicting with each other. Our study is formulated as a decision matrix (DM) that embedded mix of ten evaluation criteria and twelve diagnostic models for COVID-19. The multi-criteria decision-making (MCDM) method is employed to evaluate and benchmarking the different diagnostic models for COVID19 with respect to the evaluation criteria. An integrated MCDM method are proposed where TOPSIS applied for the benchmarking and ranking purpose while Entropy used to calculate the weights of criteria. The study results revealed that the benchmarking and selection problems associated with COVID19 diagnosis models can be effectively solved using the integration of Entropy and TOPSIS. The SVM (linear) classifier is selected as the best diagnosis model for COVID19 with the closeness coefficient value of 0.9899 for our case study data. Furthermore, the proposed methodology has solved the significant variance for each criterion in terms of ideal best and worst best value, beside issue when specific diagnosis models have same ideal best value. INDEX TERMS COVID19 diagnostic, machine learning, benchmarking methodology, chest X-rays images, entropy, TOPSIS, multi-criteria decision-making. The associate editor coordinating the review of this manuscript and approving it for publication was Zheng Xiao .

COVID-19 infection was reported in December 2019 at Wuhan, China. This virus critically affects several countries such as the USA, Brazil, India and Italy. Numerous research units are working at their higher level of effort to develop novel methods to prevent and control this pandemic scenario. The main objective of this paper is to propose a medical decision support system using the implementation of a convolutional neural network (CNN). This CNN has been developed using EfficientNet architecture. To the best of the authors’ knowledge, there is no similar study that proposes an automated method for COVID-19 diagnosis using EfficientNet. Therefore, the main contribution is to present the results of a CNN developed using EfficientNet and 10-fold stratified cross-validation. This paper presents two main experiments. First, the binary classification results using images from COVID-19 patients and normal patients are shown. Second, the multi-class results using images from COVID-19, pneumonia and normal patients are discussed. The results show average accuracy values for binary and multi-class of 99.62% and 96.70%, respectively. On the one hand, the proposed CNN model using EfficientNet presents an average recall value of 99.63% and 96.69% concerning binary and multi-class, respectively. On the other hand, 99.64% is the average precision value reported by binary classification, and 97.54% is presented in multi-class. Finally, the average F1-score for multi-class is 97.11%, and 99.62% is presented for binary classification. In conclusion, the proposed architecture can provide an automated medical diagnostics system to support healthcare specialists for enhanced decision making during this pandemic scenario.

BackgroundThe Cloud Computing paradigm offers eHealth systems the opportunity to enhance the features and functionality that they offer. However, moving patients’ medical information to the Cloud implies several risks in terms of the security and privacy of sensitive health records. In this paper, the risks of hosting Electronic Health Records (EHRs) on the servers of third-party Cloud service providers are reviewed. To protect the confidentiality of patient information and facilitate the process, some suggestions for health care providers are made. Moreover, security issues that Cloud service providers should address in their platforms are considered.ObjectiveTo show that, before moving patient health records to the Cloud, security and privacy concerns must be considered by both health care providers and Cloud service providers. Security requirements of a generic Cloud service provider are analyzed.MethodsTo study the latest in Cloud-based computing solutions, bibliographic material was obtained mainly from Medline sources. Furthermore, direct contact was made with several Cloud service providers.ResultsSome of the security issues that should be considered by both Cloud service providers and their health care customers are role-based access, network security mechanisms, data encryption, digital signatures, and access monitoring. Furthermore, to guarantee the safety of the information and comply with privacy policies, the Cloud service provider must be compliant with various certifications and third-party requirements, such as SAS70 Type II, PCI DSS Level 1, ISO 27001, and the US Federal Information Security Management Act (FISMA).ConclusionsStoring sensitive information such as EHRs in the Cloud means that precautions must be taken to ensure the safety and confidentiality of the data. A relationship built on trust with the Cloud service provider is essential to ensure a transparent process. Cloud service providers must make certain that all security mechanisms are in place to avoid unauthorized access and data breaches. Patients must be kept informed about how their data are being managed.

Research on the use of social networks for health-related purposes is limited. This study aims to characterize the purpose and use of Facebook and Twitter groups concerning colorectal cancer, breast cancer, and diabetes. We searched in Facebook ( www.facebook.com ) and Twitter ( www.twitter.com ) using the terms "colorectal cancer," "breast cancer," and "diabetes." Each important group has been analyzed by extracting its network name, number of members, interests, and Web site URL. We found 216 breast cancer groups, 171 colorectal cancer groups, and 527 diabetes groups on Facebook and Twitter. The largest percentage of the colorectal cancer groups (25.58%) addresses prevention, similarly to breast cancer, whereas diabetes groups are mainly focused on research issues (25.09%). There are more social groups about breast cancer and diabetes on Facebook (around 82%) than on Twitter (around 18%). Regarding colorectal cancer, the difference is less: Facebook had 62.23%, and Twitter 31.76%. Social networks are a useful tool for supporting patients suffering from these three diseases. Regarding the use of these social networks for disease support purposes, Facebook shows a higher usage rate than Twitter, perhaps because Twitter is newer than Facebook, and its use is not so generalized.