Background: Acne vulgaris is a chronic obstructive and inflammatory skin disease. It occurs in almost all adolescents with a prevalence of 90%. Pathogenesis of Acne vulgaris is estimated to be related to several triggering factors such as food by 23.2%, stress by 26.4%, hormones by 32.7% and use of cosmetics by 47.3%. Powder is the most widely used cosmetic in the long term and one of the causes of Acne vulgaris which causes occlusion of pores on the skin surface. In the content of powder that causes acne vulgaris because there are comedogenic ingredients such as lanolin. Methods: This study was an observational study with data collection techniques using cluster sampling and sampling technique by accidental sampling. Results: The level of knowledge of women in the Banyumas Regency was dominated by the high category as many as 64 respondents (64.0%). The incidence of acne vulgaris out of 100 respondents, 67 (67.0%) of respondents had mild acne vulgaris, 22 respondents (22.0%) had moderate acne vulgaris and 1 respondent (1.0%) had severe acne vulgaris and the rest had no acne vulgaris. Chi-square analysis showed that there was a relationship between knowledge with behavior and attitude in choosing the type of powder to the incidence of acne vulgaris as evidenced by the p value of each variable, namely 0.044 and 0.028 (p <0.05). Conclusion: the level of knowledge with behavior and attitude in choosing the powder type had a significant relationship to the incidence of acne vulgaris in women in Banyumas Regency.
Reaksi obat tidak dikehendaki (ROTD) adalah salah satu masalah kesehatan di masyarakat yang terjadi terutama pada populasi anak. ROTD pada anak dapat memiliki efek yang relatif lebih parah bila dibandingkan dengan orang dewasa. Penggunaan obat off-label merupakan faktor risiko terjadinya ROTD pada anak. Penelitian tentang penggunaan obat off-label sudah dilakukan di beberapa tempat di Indonesia tetapi sebagian besar hanya sebatas persentase penggunaan obat off-label tetapi tidak diketahui lebih lanjut tentang pengaruhnya terhadap munculnya ROTD. Tujuan dari penelitian ini adalah mengevaluasi penggunaan obat off-label dan on-label sebagai faktor risiko terjadinya reaksi obat tidak dikehendaki pada pasien pediatri. Penelitian ini merupakan penelitian studi kohor yang membandingkan reaksi obat tidak dikehendaki antara peresepan secara on-label dan off-label selama masa rawat pasien. Studi ini meneliti 130 pasien dengan jumlah penggunaan obat sebanyak 549 obat selama 4 bulan masa penelitian. Sebanyak 141 obat digunakan secara off-label dan 408 obat digunakan secara on-label. Pemberian obat off-label memiliki risiko untuk terjadinya ROTD 5,787 (Relative Risk=5,787; 95% Confidence Interval 1,072- 31,256) atau 5 kali lebih besar dibandingkan dengan pemberian obat on-label. Peneitian ini mengindikasikan bahwa pemberian obat off-label merupakan faktor risiko terjadinya reaksi obat tidak dikehendaki. Variabel perancu yang berhubungan bermakna dengan kejadian ROTD adalah variabel umur (p< 0,05).
Background: Handwashing using soap or hand sanitizer is one of the health protocols that must be implemented by society to prevent the spreading of SARS-COV2 virus which can cause pneumonia, acute respiratory syndrome and death. The implementation of health protocols during the COVID-19 pandemic caused the habit of handwashing increase. Hence, it can lead to cause irritant contact dermatitis and dry hand skin due to frequent contact with soap or hand sanitizers. Method: This study is an observational study with the sample from the villager of Banyumas regency. The data collection was taken by cluster random sampling and accidental sampling. Results: Considering the health protocol, most of the villager used to wash their hands regularly and 3 respondents (3.00%) of them did not. 100 respondents took the data and 19 respondents (19.00%) have irritant contact dermatitis and the rest did not. Furthermore, for skin hydration levels with dehydration category (0% - 29%) are 50 respondents (50.00%), normal category (30% - 50%) are 38 respondents (38.00%) and hydration category (51% - 100 %) are 12 respondents (12.00%). Chi-Square analysis showed that there was no significant relationship between handwashing habit and the incidence of irritant contact dermatitis with the value of “P” is 0.394> 0.05 and there was a significant relationship between hand washing habits and skin hydration levels with the value of “P” is 0.010 <0, 05. Conclusion: Handwashing habits have a significant relationship to skin hydration levels.
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