Infantile malignant osteopetrosis (IMO; OMIM 259700) is a rare inherited bone disease characterized by reduced or dysregulated activity of osteoclasts, resulting in generalized osteosclerosis. The disease usually presents within the first few months of life with anemia, hepatosplenomegaly, frontal bossing, nystagmus, blindness, deafness, and bone fractures. Children with IMO are at risk of developing hypocalcemia, with attendant tetanic seizures. We report the case of a baby boy who presented with neonatal hypocalcemia. Skeletal radiographs demonstrated sclerotic bones and a dense base of the skull with typical "space alien" face confirming the diagnosis of IMO. Pancytopenia developed at 2 months of age. Visual evoked potential showed severe bilateral optic nerve damage. Genetic mutation study revealed a new mutation in exon 13 of the TCIRG1 gene. Neonatal hypocalcemia can occur as result of IMO, which is easily missed out by clinicians. This causes delay in establishing the diagnosis and starting necessary treatment. Therefore, osteopetrosis should be kept in mind as a rare cause of neonatal hypocalcemia.
The aim of this study was to determine the frequency of tinea pedis and manuum (dermatophyte infections of the hands and feet) in adults in rural areas of Turkey, the risk factors and self-administered treatment options. A total of 2,574 people living in a rural area were enrolled in the study. Participants were asked demographic data, hygienic habits in a questionnaire. KOH preparations and culture were performed from suspicious lesions. Medical and alternative therapy methods and former dermatophytosis diagnosis history were taken from the respondents with suspicious lesions. Microbiological samples were taken from 285 (11.1%) participants. Culture was positive in 109 (4.2%) of those. The most common agent was Trichophyton rubrum. The predisposing factors were found as age older than 40, male gender and obesity. Forty-nine (44.9%) of patients had taken a medical therapy, 56 (51.4%) had performed non-medical methods (cologne, Lawsonia inermis-Henna and softener creams). Patient's education about the treatment compliance is important.
Background: Adolescent Food Habit Checklist (AFHC) is an instrument designed to measure eating behaviours of adolescents. The aim of the study was to adapt AFHC for the Turkish cultural settings and evaluate its� reliability and construct validity. Methods: Forward and backward translations were carried out and Turkish version of the AFHC was generated. AFHC was administered to 347 students attending second grade primary school. Validity and reliability analyses were used for the assessment of the study data. Results: Four item with the inter-item correlation below 0,2 was eliminated from Turkish version of AFHC. The final instrument consist of 19 items, evaluating consumption of sugar (4 item), fat (6 item), fruit-vegetable (6 item), carbohydrate and fast food (2 item) and general diet (1 item). The inter-item correlation of these items were between 0,21 and 0,46. The instrument was internally consistent, with Cronbach's alpha-coefficients of 0,718. There was positive correlation with test-retest reliability ( r=0.854; p<0.001). AFHC scale score of obese, overweight adolescents were (8,74±4,03) lower than normal weight (10,53±3,39) adolescents ( p=0.003). Boys (9.22±3.46) had lower scale scores than girls (11.18±3.42) ( p<0.001) demonstrating construct validity. Conclusions: The Turkish version of AFHC questionnaire is reliable and valid measure evaluating Turkish adolescents eating behaviours. [TAF Prev Med Bull 2012; 11(1.000): 49-56
ÖzetAmaç: Çalışma, bir hastanedeki sağlık çalışanlarının kesici delici aletleri güvenli kullanımına ilişkin tutumlarını ölçmek amacıyla planlandı. Yöntemler: Kesitsel tipte olan bu çalışmanın evrenini Haseki Eğitim ve Araştırma Hastanesi sağlık çalışanları oluşturmuş, hastane yöneticisinden gerekli izinler alınmıştır. Hastanede toplam 1135 sağlık çalışanı görev yapmakta olup, çalışmaya katılmayı kabul eden 539 sağlık çalışanında yapılmıştır. Çalışmada Uzunbayır ve ark. tarafından geliştirilen (Cronbach alfa=0,80) "Sağlık Çalışanlarının Kesici-Delici Tıbbi Aletleri Güvenli Kullanımına Yönelik Tutum Ölçeği" kullanılmıştır. Verilerin değerlendirilmesinde SPSS paket programı ile t testi ve Anova analizi kullanılmıştır. Bulgular: Katılımcıların %17,1'i doktor, %58,4'ü hemşire, %24,5'i temizlik personeli olup, grubun %43,8'i cerrahi bir bölümde çalışmaktaydı. Personelin %25,8'i mesleğinin ilk beş yılını bitirmiş idi. Meslek gruplarına göre alt ölçek bölümlerinden alınan puanlar karşılaştırıldığında; bilişsel bölüm ile meslek grupları arasında (p=0,810) ve duyuşsal bölüm ile meslek grupları arasında bir fark bulunamadı (p=0,401). Hemşirelerin davranışsal puan ortalamalarının, doktor ve temizlik personeline göre daha yüksek olduğu saptandı (p=0,000). Sonuç: Cerrahi bölümlerde çalışanlarda, beş yılın üstünde mesleki tecrübesi olanlarda ve hemşirelerde ölçek puanı yüksek bulunmuş, kesici-delici tıbbi aletleri diğer gruplara göre daha güvenli kullandıkları saptanmıştır. Uzunbayır et al. (Cronbach's alpha=0.80). Statistical analysis was performed using SPSS 21.0 and data were analyzed using the t-test and ANOVA. A p value of less than 0.05 was considered significant. Results: 17.1% of participants were doctors, 58.4% -nurses, 24.5% -cleaning staff and 43.8% of subjects were working in a surgical department. 25.8% of participants had at least 5 years of working experience in this field. There were no significant differences between the occupational groups in cognition (p=0.810) and affect scores (p=0.401). It was found that the behavioral scores in nurses were higher than in doctors and cleaning staff (p=0.000). Conclusion: The total score was found to be higher in nurses as well as in participants working in a surgical department and those having at least 5 years of professional experience. It was determined that these groups used the medical instruments more safely than did the other ones. (The Me di cal Bul le tin of Ha se ki 2014; 52:168-71)
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.