The findings of this study suggest that increased oxidative stress, increased lipid peroxidation and an imbalance in the antioxidant defence system may be involved in the pathogenesis of LP.
Aim: The purpose of the present study was to investigate whether total antioxidant capacity (TAC) and total oxidant status (TOS) are associated with major depressive disorder (MDD) and to evaluate the impact of antidepressant treatment on TAC and TOS in MDD.
Methods: Fifty‐seven MDD patients and 40 healthy controls participated in the study. Serum TAC and TOS were measured both in patients and controls using Erel's methods. Patients were treated with antidepressant drugs for 12 weeks. The treatment course was evaluated using the Montgomery–Asberg Depression Rating Scale (MADRS) in all patients.
Results: TOS and oxidative stress index (OSI) were higher (P = 0.0001 for both) and TAC was lower (P = 0.0001) in the MDD group compared with those of the controls. After 3 months of antidepressant treatment, TOS and OSI were decreased and TAC was increased compared with the pretreatment values (P = 0.0001, for all). Furthermore, there were significant positive correlations between the severity of the disease and serum TOS and OSI (r = 0.584, P = 0.0001; r = 0.636, P = 0.0001, respectively). A negative correlation was found between the severity of the disease and serum TAC (r = −0.553, P = 0.0001) at the pre‐treatment stage.
Conclusion: Treatment administered for 3 months to MDD patients increases TAC while decreasing TOS and OSI.
Obesity is associated with morphologic alterations in left ventricle and left atrium and subclinical changes in left ventricle systolic function which can be detected by strain and strain rate imaging even without overt heart disease.
The aim of this study was to evaluate the surface tension values of established and potential endodontic irrigants to which a surface active agent had not been added. Additionally, Cetredixine, a surfactant-containing 0.2% chlorhexidine gluconate solution, was included in the measurements. Surface tension measurements were performed using the ring method on a DuNouy tensiometer at a standard room temperature. Ringer's solution, saline solution, and distilled water had the highest surface tension values, whereas those of NaOCl (2.5% and 5%) and 17% EDTA were relatively low. Two anesthetic solutions, Ultracaine and Citanest, demonstrated values similar to NaOCl and EDTA, although a statistically significant difference was found between all solutions tested. Cetredixin displayed the lowest surface tension. A low surface tension agent should penetrate tubules better.
A An na ah ht ta ar r K Ke el li im me el le er r: : Faktör analizi, istatistiksel; biyometri; anketler; sonuçların yeniden üretilebilirliği A AB BS ST TR RA AC CT T In natural and applied, social, and health sciences, testing the structural validity of scale adaptation and development studies is important. The testing of validity is based on the rational of testing the structure by data built on two variables, basically, data measured directly (manifest) and not measured directly (latent). This study investigated Confirmatory Factor Analysis (CFA). CFA, involving a theoretical structure, is a type of Structural Equation Models (SEM) and in practice is a difficult analysis method. Additionally while testing the model with the data, fit indices that demonstrate the compliance of the model were included. In this study using the data obtained by the Children's Eating Behavior Questionnaire (CEBQ), different models suggested by the LISREL program were tested and the models were improved. Data obtained by Children's Eating Behavior Questionnaire in parents (n=468) of children presenting to the Department of Pediatrics, Faculty of Medicine, Gaziosmanpaşa University between May-June 2008 and of kindergarten students in Tokat were used to apply DFA and Fit Indexes. The results of CFA in a study with favorable Explanatory Factor Analysis (EFA) values are worse than the results of EFA. According to the results of 5 models produced by the corrections suggested by the Lisrel program, the fit indexes produced by the model were shown to be corrected. When testing the structural validity, the results of EFA, which is a descriptive analysis, by CFA and correcting the model if required will improve the model.
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