database contains 4,153,588 pharmacy-dispensed claims with 112,523 ingredient entries and 16,944,271 physician-dispensed claims with 2,222,342 ingredient entries. The average amount paid per CD ingredient per year for pharmacy-dispensed CDs increased by 37% from 2011 to 2012 and 67% from 2012 to 2013, while physiciandispensed increased by 14% from 2011 to 2012 and 20% from 2012 to 2013. The current CA AB 378 regulation does not significantly reduce CD cost, in fact the cost increased. The change in cost of CD using the alternative Colorado pricing scheme is lower. In 2011, mean CA CD cost (pharmacy-dispensed after combining all ingredients

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