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Four patients with erythropoietic protoporphyria (EPP) are reported, in whom oral iron produced clear-cut clinical and biochemical deterioration. This suggests that there are two biochemically and genetically distinct sub-groups of EPP patients distinguished by their dramatically different response to oral iron.

THIS is a study of the bacterial colonisation of the skin of the newborn during the first days of Me. Although some information concerning pathogens in the newborn and infant is available (Jellard, 1957;Hurst, 1960; Simpson, Tozer and Gillespie, 1960; Light, Sutherland and Schott, 1965), the time-course of the colonisation of the skin by pathogenic and non-pathogenic micro-organisms has not been investigated in detail (Hurst, 1965). The aim of our work was to discover whether any organisms were present on the skin at the time of birth, the relation of any bacteria found to the flora in the birth canal of the mother and the subsequent behaviour and changes of the flora of the skin. We studied the bacterial flora of the skin in 29 babies at the moment of birth and 225 babies during the first 29 hr of life. Cultures were taken on several occasions from each of five sites on each baby and a total of several thousand results was obtained. H (1) J. PAIH. BACT.-VOL 95 (1968)

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