Attention -deficit / hyperactivity disorder is a common neurodevelopmental disorder in childhood, for which there are several different treatment options. Among the suggested medications, methylphenidate (a central nervous system stimulant) is the first option in the treatment of ADHD. Psychostimulants are associated with various vascular problems including peripheral vasculopathy. This report describes two patients with ADHD who developed Raynaud's phenomenon during the modified-release methylphenidate treatment.

No abstract

No abstract

Supplemental digital content is available in the text.

Introduction: Genetic and environmental factors are thought to play a role in the etiology of autism spectrum disorder. Studies on vaccination, which is one of the environmental factors, suggest that there is no relationship between vaccines and autism development. However, a part of society still believes that vaccines lead to autism. Therefore, we aimed to investigate the distribution and reliability of the articles on the internet, which is the first place to which families refer for information about this subject. Methods: In this study, we searched the term autism vaccine in Google's version for Turkey. The information on each website was grouped as accurate, incorrect, and contradictory. We used the JAMA score, a standard indicator of health information quality, to assess the basic reliability index of the article. The JAMA score takes into account whether a website declares an author, the date of writing, financial ownership, and whether the information is supported by references. Results: A total of 124 websites were listed as a result of this search. When irrelevant and inaccessible sites were removed, 102 web pages were evaluated. The information obtained from 76 (74.5%) websites was accurate, 20 (19.6%) websites contained incorrect information, and 6 (5.9%) presented contradictory information. Although the JAMA score of the sites containing the accurate information was higher than the sites with incorrect information, the difference between them was not statistically significant. In terms of the information given in the content of the internet sites, it was found that six of the top ten sites were accurate, three were incorrect, and one was contradictory. No statistically significant relationship was found between the accuracy of the information and the ranking of the sites. Discussion and Conclusion: These results show that accurate information is not listed primarily in the top positions, and that information about autism and vaccination has similar distribution. It is important to increase the number of articles and projects aimed at informing society about autism and vaccination through the internet by scientists and government officials and to ensure that families have access to accurate information