Pseudomonas aeruginosa
is an opportunistic pathogen that forms biofilms during infection, resulting in recalcitrance to antibiotic treatment. Biofilm inhibition is a promising research direction for the treatment of biofilm-associated infections.
Pseudomonas aeruginosa
can form biofilms at the site of burn wound, leading to infection and the failure of treatment regimens. The previous
in vitro
study demonstrated that a combination of the quorum-quenching enzyme AidH
A147G
and the extracellular matrix hydrolase PslG was effective in inhibiting biofilm and promoting antibiotic synergy.
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