amount of the drug she remained comfortable and free of pain in the extremities. However, diarrhea developed. When treat¬ ment with the drug was discontinued, pain in the legs returned and the diarrhea stopped. When the drug was again given the diarrhea returned and the pain in the legs stopped. She chose to have the diarrhea rather than the pain. Twelve days after admission she was transferred to an orthopedic hospital completely relaxed and free of pain. At the termination of her pregnancy, in October, she delivered a normal baby boy. COMMENT At the present time there is no form of treatment in acute poliomyelitis that limits the spread of virus in the central nervous system or alters its effect on the nerve cells. Many patients recovered completely with¬ out treatment hut others, despite heroic measures, suffer extensive paralyses.

larger than the number taking placebos was because many of the patients were in such extreme circumstances that placebo therapy was not justified.There is evidence that not all the patients took the

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