Objective To assess the changes in antim€ ullerian hormone (AMH) levels after ablation for symptomatic uterine fibroids and adenomyosis using ultrasound-guided high-intensity focused ultrasound (USgHIFU).Design A prospective study.Setting Gynaecological department in multiple hospitals in South Korea.Population Patients with uterus fibroids and adenomyosis.Methods Seventy-nine women with symptomatic uterine fibroids and adenomyosis who met the inclusion criteria were enrolled in our study between January 2014 and December 2014. All patients underwent USgHIFU ablations. Each patient was examined before and after treatment, and at 6 and 12 months after treatment by T2-weighted MRI imaging (T2WI) and T1-weighted MRI imaging (T1WI) with gadolinium injection. Symptom severity scores (SSS), Uterine Fibroid Symptom Quality of Life (UFS-QOL) questionnaire subscales, and reductions of treated volume were assessed. AMH levels before and 6 months after HIFU ablation were compared to determine whether USgHIFU ablation affected ovarian reserve.Main outcome measures HIFU treatment did not affect the ovarian function.Results HIFU treatment time (mean AE standard deviation), HIFU ablation time, and treatment energy were 73.5 AE 25.6 minutes, 9994.7 AE 386.8 seconds, and 364 713.8 AE 156 350.7 Joules, respectively. AMH levels before and 6 months after HIFU ablation were 2.11 AE 2.66 and 1.84 AE 2.57 lg/l, respectively. There was no significant difference in AMH level between the two time points (P > 0.05).Conclusions USgHIFU ablation for uterine fibroid and adenomyosis was effective without affecting ovarian reserve.

As the sample size of our study was small, the conclusions could be biased. Nevertheless, our findings show that PTB causes a significant decline in lung function even in localised PTB, whereas advanced PTB was associated with excessive or even higher decline. This study suggests that early diagnosis and treatment of PTB is needed to preserve lung function.

The soft optic mode spectra of monoclinic I lanthanum pentaphosphates LnP5O14(Ln = La, Ce, Pr, Nd, Sm, Eu, Gd, Tb) are measured in the range of 20-300℃. The Ag-B2g and Ag-Ag soft modes in different LnP5O14 all soften to 20 cm-1 at ferroelastic transition temperature Tc. Another Bg-B3g soft mode softens to 38cm-1 at Tc. The coupling of Ag-B2gsoft mode with e5, plays an essential role in the phase trasition and the temperature dependence of soft-mode intensity can be described by means of the bilinear mode-coupling model. The increment of Tc from La to Tb in this system is owing to the lanthanum contraction.

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