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Context: Plyometric exercise has been recommended to prevent lower limb injury, but its feasibility in and effects on those with functional ankle instability (FAI) are unclear.Objective: To investigate the effect of integrated plyometric and balance training in participants with FAI during a singlelegged drop landing and single-legged standing position.Design: Randomized controlled clinical trial. Setting: University motion-analysis laboratory.Patients or Other Participants: Thirty athletes with FAI were divided into 3 groups: plyometric group (8 men, 2 women, age ¼ 23.20 6 2.82 years; 10 unstable ankles), plyometricbalance (integrated)-training group (8 men, 2 women, age ¼ 23.80 6 4.13 years; 10 unstable ankles), and control group (7 men, 3 women, age ¼ 23.50 6 3.00 years; 10 unstable ankles).Intervention(s): A 6-week plyometric-training program versus a 6-week integrated-training program.Main Outcome Measure(s): Postural sway during singlelegged standing with eyes open and closed was measured before and after training. Kinematic data were recorded during medial and lateral single-legged drop landings after a 5-second single-legged stance.Results: Reduced postural sway in the medial-lateral direction and reduced sway area occurred in the plyometricand integrated-training groups. Generally, the plyometric training and integrated training increased the maximum angles at the hip and knee in the sagittal plane, reduced the maximum angles at the hip and ankle in the frontal and transverse planes in the lateral drop landing, and reduced the time to stabilization for knee flexion in the medial drop landing.Conclusions: After 6 weeks of plyometric training or integrated training, individuals with FAI used a softer landing strategy during drop landings and decreased their postural sway during the single-legged stance. Plyometric training improved static and dynamic postural control and should be incorporated into rehabilitation programs for those with FAI.Key Words: plyometric training, balance training, landings, ankle injuries Key PointsAfter 6 weeks of isolated plyometric or combined plyometric and balance training, people with functional ankle instability demonstrated increased lower extremity maximal sagittal-plane angles and decreased maximal frontalplane and transverse-plane angles on ground contact. Static and dynamic postural control improved with plyometric training, which should be included in rehabilitation programs for patients with functional ankle instability.