Objectives
It is vital to determine the intensive care unit (ICU) requirement at an early stage to reduce the mortality rate in COVID-19 patients. The aim of the study was to find reliable predictive markers to determine the ICU requirement.
Methods
We retrospectively reviewed the clinical and laboratory records of 151 COVID-19 patients. The predictive abilities of biochemical parameters and computed tomography (CT) score were evaluated to determine of ICU requirement.
Results
The area under curve (AUC) values for procalcitonin, D-Dimer, C reactive protein (CRP), glucose, lactate dehydrogenase (LDH) and CT score were found higher than those for other parameters in the prediction of ICU requirement. The negative predictive values of these markers were higher than their positive predictive values. CT score was found to be highly correlated with fibrinogen and CRP. The glucose levels [odd ratio (OR): 95% CI; 1.07, p-value: 0.014] and CT score [OR: 95% CI; 1.05, p-value: 0.022] were associated with ICU requirement in COVID-19 patients.
Conclusions
CT score, procalcitonin, D-Dimer, CRP, glucose, and LDH are potential predictors to rule out ICU requirement on hospital admission. Fibrinogen and CRP can be used to follow up and predict lung damages in patients with COVID-19.
, which has recently become a worldwide pandemic with high mortality, causes severe pneumonia. The major routes of transmission of this disease are direct inhalation of respiratory droplets or contact with surfaces contaminated with them. Its definitive diagnosis is made by a real-time PCR test. Radiological methods, especially computed tomography (CT), play an important role in supporting the diagnosis and determining disease stage and complications. In this paper, we report the CT findings of COVID-19 pneumonia at different disease stages in a patient diagnosed with the disease, and we provide a discussion of the relevant literature.
The spleen is an important organ of reticuloendothelial system, but it is a less well-known organ in terms of its pathologies. Therefore, the spleen is considered a 'forgotten or neglected organ' by radiologists and clinicians. Spleen pathologies show a wide spectrum ranging from congenital anomalies to malignant lesions. Radiological imaging methods play an important role in detecting these pathologies.
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