Glaucoma is an optic neuropathy characterized by progressive loss of retinal ganglion cells (RGCs) and their axons, eventually resulting in visual field loss. As glaucomatous visual misfortune is irreversible, early determination is significant; be that as it may, this can be trying because of enormous between singular variety in ordinary plate appearance, between onlooker contrasts in circle assessment, and absence of affectability of visual field testing because of physiological excess in retinal ganglion cell responsive fields. The reason for this investigation is to decide the symptomatic exhibition of macular ganglion cell-internal plexiform layer (GCIPL) thickness and to contrast it and that of peripapillary retinal nerve fiber layer (RNFL) thickness to segregate typical eyes and eyes with early glaucoma. 20 eyes with early glaucoma (case gathering) and 20 ordinary eyes (control gathering) were joined up with this examination and their RNFL and GCIPL boundaries were estimated utilizing Topcon 3D ghostly space OCT 2000. the GCIPL and RNFL were more slender and the vertical cup-to-circle width proportion was bigger in subjects with glaucoma than in typical subjects. What's more, aggregate and sub-par GCIPL values were the most exact for the analysis of early glaucoma. high hazard gathering and analyzed gathering of glaucoma ought to be catch up with RNFL and GCIPL thickness utilizing OCT.
Glaucoma is an optic neuropathy characterized by irreversible loss of neural tissue over time, Advancement in OCT technology has provided an objective and quantitative method to evaluate RNFL and optic nerve head which is clearly advantageous in the effective management of patients, both in terms of diagnosis and monitoring of response to therapy. to discuss the most important glaucoma-related applications of OCT A total of 48 eyes of participants were classified into 4 groups: patient with Family history of Primary open angle glaucoma(11 eyes), patients with Ocular hyper tension (13eyes), patients with black race (12eyes) and patients with high myopia (12eyes), All study subjects will undergo complete ophthalmic examination, clinical evaluation of optic disc and Spectral domain OCT system. the mean ±SD age of the studied group was 52.2±20.2 and 66.7% of them were males while 33.3% of them were females. Glaucoma was found in 62.5% of the examined high risk group while 37.5% of them were not glaucomatous, a statistically significant difference is found only in average RNFL thickness between normal group and glaucomatous group.
Background:Keratoconus (KC) is a progressive disorder with conical deformity of the cornea. It is characterized by corneal thinning induces irregular astigmatism, myopia and protrusion resulting in mild to marked impairment in the quality of vision. Aim of work : Measuring posterior corneal elevation in normal and keratoconus corneas using pentacam to discriminate keratoconus from normal corneas and to compare and correlate anterior corneal elevation maps and posterior corneal elevation maps with severity of keratoconus. Methods: This study included 50 participants, 25 KC patients and 25 healthy subjects. All cases were submitted to evaluation in the form of: history taking, visual acuity testing (UCVA, BCVA), slit lamp examination, corneal topography. Results: The comparison of keratometric and pachymetric readings showed significant differences between the study and control groups, central astigmatism (frontal and back), Kmax, KI, ISV and IVA show statistically significant difference between normal and keratoconic eyes. Posterior surface of the cornea shows statistically significant difference between normal and keratoconic eyes, In all keratoconus stages, the Posterior corneal elevation was significantly higher than the anterior corneal elevation by increasing in the keratoconus severity. Conclusion: Our data support the hypothesis that the posterior corneal surface contributes to the early topographical manifestation of keratoconus in keratoconus eyes. Although the diagnostic sensitivity was not explicitly evaluated in our study, giving more attention to posterior surface parameters may facilitate the early detection of keratoconus corneas.
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