Background: The aim of this study is to analyze the work of
the interdisciplinary Brain Tumor Board (BTB) which was established
at Freiburg University Hospital in 1998. Patients
and Methods: From January 1998 to December 2003, a total
of 1,516 patients were discussed in 259 meetings of the BTB.
The protocols of the BTB were analyzed retrospectively. Results:
In 79% of the patients, the diagnosis was based on
histological findings or a typical radiological appearance of
a lesion, or both. This group was composed of 4 subgroups:
28% benign skull base tumors (19% meningiomas, 4% pituitary
adenomas, 3% acoustic schwannomas, 2% others),
24% primary brain tumors of glial origin (8% glioblastomas,
12% gliomas other than glioblastomas, 5% oligoastrocytomas
or oligodendrogliomas), 19% brain metastases, and
8% other brain or skull base tumors. In 13% of the cases, the
exact diagnosis was still unknown when the patient was
presented. 8% of the presentations were motivated by nontumorous
interdisciplinary problems (e.g. arterio-venous
malformations). The recommendations given by the BTB included:
23% further diagnostic procedures (11% non-invasive
examinations, 12% stereotactic biopsies), 57% active
antitumoral therapy (22% resection, 17% fractionated radiotherapy,
13% radiosurgery, 5% chemotherapy, <1% embolization),
20% no treatment (14% watchful waiting, 6%
supportive care). 91% of the BTB recommendations were realized
within 3 months. Conclusion: Interdisciplinary care
seems to be particularly necessary in patients with benign
skull base tumors, gliomas and brain metastases. Decisions
made in a small interdisciplinary group of experts have a
high potential of subsequently being realized.
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