No abstract

Radiographic examinations combined with clinical and histological tests play an important role in diagnosing changes in the craniofacial region. Considering that X-radiation is a form of ionizing energy capable of damaging the DNA of individuals, it has been the object of studies since its introduction. The micronucleus test is used to quantify this damage, assessing whether or not chromosomal breakage occurs. Objective: To evaluate, through a systematic review (SR) with meta-analysis, the occurrence of genotoxic effects in the oral epithelium after the exposure of patients to panoramic radiographs. Methods: An SR was performed with the PICOS (Population, Intervention, Comparison, Outcome, and Study design) strategy, aiming to answer the following question: “Can panoramic radiographs induce genotoxic effects on the oral epithelium?” The study was registered in the PROSPERO (International prospective register of systematic reviews) platform. A systematic search was performed in the following electronic databases: PubMed (including MedLine), Scopus, Embase, LILACS, Medline EbscoHost, and Google Scholar. Treatment effects were defined as standardized mean difference (SMD), and 95% confidence intervals (CI) were established. The Joanna Briggs Institute questionnaire for observational studies was applied to assess the risk of bias. The GRADE tool was used to assess the quality of evidence of the SR. Results: A total of 251 potentially relevant studies were selected through the search strategy. After screening titles and abstracts, 11 full-text manuscripts were assessed for eligibility and nine observational studies were included in the meta-analysis. The present study showed an increase in micronuclei after the exposure (SMD = 0.21, 95% CI, 0.03 to 0.28, p = 0.02), with a Tau2index = 0.00, Chi2 = 2.35, and p-value = 0.97. Therefore, the articles selected were considered homogeneous and the I² of 0% indicated low heterogeneity. Conclusion: According to the studies analysed, although the quality of evidence was considered low, panoramic radiographs can cause genotoxic damage in the oral epithelium but with a small effect size.

Objetivo: Analisar como a disponibilidade dos implantes pelo Sistema Único de Saúde (SUS) contribui para a melhora e promoção de saúde. Métodos: Trata-se de uma revisão integrativa, feita entre setembro e dezembro de 2022, nas bases de dados SCIELO, LILACS, BVS e pelo mecanismo de busca do Google Acadêmico, com auxílio dos Descritores em Ciências da Saúde (DeCS): Implante Dentário, Sistema Único de Saúde, Políticas de Saúde, Serviços de Saúde Bucal. Os critérios de inclusão: estudos em português e inglês, no período entre 2016 e 2022 e gratuitos. Os critérios de exclusão: trabalhos incompletos ou duplicados, teses, resumos, resenhas e estudos fora do escopo. Após as buscas e triagem, 10 artigos foram escolhidos para compor a amostra final. Resultados: Em dezembro de 2010, o SUS passou a financiar procedimentos de implante dentário osteointegrado e prótese dentária sobre implante. O tratamento proporciona, estabilidade dentária, reestabelecimento da mastigação, estimula a regeneração óssea, melhora da fala, impedimento de futuras doenças relacionadas ao uso de próteses, e por fim, repõe o sorriso. Considerações finais: Ao ofertar implantes dentários osteointegrados a qualquer usuário brasileiro, o SUS promove a saúde, em virtude da melhora da qualidade de vida do paciente, em geral.

Introduction General anesthesia is commonly used in the dental treatment of people with disabilities, anxious or difficult behavior, who need complex and/or extensive treatments. Objective The aim of this study was to evaluate the epidemiological profile of patients with disabilities undergoing dental treatment under general anesthesia by the team of the Dental Unit for Patients with Special Needs of the Federal University of Sergipe. Material and method Through the analysis of 371 dental records of patients assisted between August 2002 and March 2019. Result The analysis showed that 56.1% of patients were male, the most prevalent age group was 11-20 years, and the most frequent medical conditions were intellectual disability, followed by multiple disabilities. Relative to dental procedures, in 94.1% of the patients, it was observed that 4,056 dental extractions were performed and in 52.3% of patients, 1,156 restorations were performed. In 30.2% of patients, total multiple extractions were performed. Radiographic examination was performed in 51.8% of patients. As regards the origin of patients, 58.8% were from municipalities in the state, other than the capital. Return to the service for follow-up and prevention was observed in 38.5% of patients. Conclusion There is great need for early dental intervention, with specific preventive actions for this group of patients, focusing on those from interior regions of the state.

A Doença de Niemann-Pick (DPN) é uma doença autossômica recessiva causada por um distúrbio no metabolismo do lipídio e pela deficiência total ou parcial da enzima esfingomielinase ácida. Esta deficiência resulta no depósito patológico da esfingomielina