We describe the case of a 63-year-old woman who developed a coronavirus disease 2019-associated acute encephalopathy with perivascular gadolinium enhancement. ABBREVIATIONS: ICU ¼ intensive care unit; PRES ¼ posterior reversible encephalopathy syndrome; SARS-Cov-2 ¼ Severe Acute Respiratory Syndrome coronavirus 2 A 63-year-old woman was admitted to our hospital on day 7 (day 1 is the first day of symptoms) with fever, dry cough, fatigue, and subjective dyspnea. A nasopharyngeal swab for Severe Acute Respiratory Syndrome coronavirus 2 (SARS-Cov-2) was positive. Arterial blood gas analysis in room air showed mild hypocapnia (partial pressure of carbon dioxide, 31), causing mild respiratory alkalosis (pH ¼ 7.48) and a low level of oxygen (partial pressure of carbon dioxide, 67). A chest x-ray was performed, showing bilateral ground-glass opacities. The patient had hypertension, but no other comorbidities were identified. She was first admitted to the emergency ward and treated with a continuous positive airway pressure helmet; lopinavir/ritonavir was started as compassionate use approved by the ethics committee, as well as empirical piperacillin-tazobactam. Her respiratory parameters progressively worsened during the next days until she showed dyspnea, and her PaO2/FiO2 ratio was 110 with a continuous positive airway pressure helmet at 15 cm of water and an inspiratory fraction of oxygen of 70%. On day 11, she was intubated and transferred to the intensive care unit (ICU). During her ICU stay, she initially received mechanical ventilation at a medium level of positive end-expiratory pressure (up to 14) and inhaled nitric oxide and underwent two 20-hour
• High SUV is a poor prognostic factor in HNSCC • High ADC is a poor prognostic factor in HNSCC • In patients with high SUV , high ADC identified those with worse prognosis.
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