IMPORTANCE Type 2 diabetes is expected to accelerate age-related peripapillary retinal nerve fiber layer (pRNFL) loss, but limited information on the rate of reduction in pRNFL thicknesses in patients with type 2 diabetes is available. OBJECTIVE To investigate longitudinal changes in pRNFL thickness in patients with type 2 diabetes, with or without diabetic retinopathy (DR). DESIGN, SETTING, AND PARTICIPANTS A total of 164 eyes of 63 healthy individuals and 101 patients with type 2 diabetes (49 patients without DR [non-DR group] and 52 patients with mild to moderate nonproliferative DR [NPDR group]) were enrolled in this prospective,
Abstract-This paper presents a game-theoretic scalable offloading system that provides seamless video streaming services by effectively offloading parts of video traffic in all video streaming services to a WiFi network to alleviate cellular network congestion. The system also consolidates multiple physical paths in a cost-effective manner. In the proposed system, the fountain encoding symbols of compressed video data are transmitted through long term evolution (LTE) and WiFi networks concurrently to flexibly control the amount of video traffic through the WiFi network as well as mitigate video quality degradation caused by wireless channel errors. Furthermore, the progressive second price auction mechanism is employed to allocate the limited LTE resources to multiple user equipment in order to maximize social welfare while converging to the ε-Nash equilibrium.Specifically, we design an application-centric resource valuation that explicitly considers both the realistic wireless network conditions and characteristics of video streaming services. In addition, the scalability and convergence properties of the proposed system are verified both theoretically and experimentally. The proposed system is implemented using network simulator 3. Simulation results are provided to demonstrate the performance improvement of the proposed system.
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