Irrespective of the cause of the observed differences in serum creatinine concentrations between the study patients and controls, the serum creatinine concentration should clearly be interpreted with caution in patients with rheumatic diseases. Perhaps lower normal or reference values should be used in such patients and in other patients with atrophic muscles. 1 Brochner-Mortensen J. A simple method for the determination of glomerular filtration rate. Scand]3 Clin Lab Invest 1972;30:271-4. 2 Fabiny DL, Ertinghausen G. Automated rate-reaction method for determination of serum creatinine with the Centri-Chem. ClGn Chem 1971 ;17:696-700. 3Granerus G, Aurell M. Reference values for 51Cr-EDTA clearance as a measure of glomerular filtration rate. Scandj3 Clin Lab Invest 1981;41: 611-6. Jungner I, Jungner G. Creatinine and creatine clearance in the acute stage of paralytic poliomyelitis. Acta Med Scand 1960;166:357-68.
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