Organosoluble extracts from 55 Turkish medicinal plants were tested under standardised conditions for biological activity against third-instar larvae of mosquitoes Aedes aegypti and Anopheles gambiae. Eight extracts demonstrated significant larvicidal activity, with An. gambiae being more susceptible than Ae. aegypti in all cases. The possibility of using indigenous plants for mosquito control is discussed.Resume-^-Des extraits organosolubles provenant de 55 plantes medecinales de Turquie ont et£ tested sous conditions standardises pour leur activity biologique sur des larves du 3e stade d'Aedes aegypti tt Anopheles gambiae. Huit extraits ont de'montre' une activity larvicide significative, avec An. gambiae e*tant plus susceptible qu'Ae. aegypti dans tous les cas. Les possibility d'utilisation des plants indigenes pour la lutte contre moustiques a tt€ discut£e.
Turkey has an extraordinarily rich flora and wide knowledge of their indigenous medicinal plants. Medicinal plants constitute an important componbnt of flora and are widely distributed in different floristic regions of Turkey. Historically, plants have supplied the chemistry for over 25 % of prescription drugs used in human medicine ( 1) and such biologically active plants have also provided leads to natural insecticides(2). Accordingly, we are investigating the potential of Turkish medicinal plants as a resource of new chemistry for public health and plant protection. The biological evaluation of substances from plant sources is highly releavant for the identification of lead compounds which can result in the development of novel and safe medicinal agents. During our extensive studies with Turkish medicinal plants, we have isolated and characterized a large number of natural products. On the other hand, a more systematical approach to the discovery of drugs from these plants has been initiated using bioassay-guided fractionation. At the end of this fractionation of selected plant extracts has resulted in the identification of active compounds representing a wide range of structures, including alkaloids, terpenoids and phenolic compounds(3). Fifty five organosoluble extracts prepared from Turkish medicinal plants were investigated for their biological activities against insects, nematodes, plant pathogens and brine shrimp in addition to their biological activities such as antimalarial, anticholinergic, analgesic and antiplatelet activities.
Probiotics have been defined as “living microorganisms that create health benefits in the host when taken in sufficient amounts. Recent developments in the understanding of the relationship between the microbiom and its host have shown evidence about the promising potential of probiotics to improve certain health problems. However, today, there are some confusions about traditional and new generation foods containing probiotics, naming and classifications of them in scientific studies and also their marketing. To clarify this confusion, the Food and Drug Administration (FDA) declared that it has made a new category definition called "live biotherapeutic products" (LBPs). Accordingly, the FDA has designated LBPs as “a biological product that: i)contains live organisms, such as bacteria; ii)is applicable to the prevention, treatment, or cure of a disease/condition of human beings; and iii) is not a vaccine”. The accumulated literature focused on LBPs to determine effective strains in health and disease, and often focused on obesity, diabetes, and certain diseases like inflammatory bowel disease (IBD).However, microbiome also play an important role in the pathogenesis of diseases that age day by day in the modern world via gut-brain axis. Herein, we discuss the novel roles of LBPs in some gut-brain axis related conditions in the light of recent studies. This article may be of interest to a broad readership including those interested in probiotics as LBPs, their health effects and safety, also gut-brain axis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.