Our findings show, in MS patients with stable neurological impairment and no recent disease exacerbation, a correlation between smell loss and the lesion load in the regions of the brain involved in olfaction and support the theory that the extent and severity of MRI abnormalities in specific brain regions are related to the presence of selective neurologic and neuropsychologic impairment.

Robustness of nominal Global Navigation Satellite Systems (GNSS) performance can be enhanced by means of complimentary systems, such as the Long Term Evolution (LTE). Particularly, the LTE standard specifies a dedicated downlink signal for positioning purposes, i.e. the positioning reference signal (PRS). This paper presents the achievable localization accuracy of the PRS signal for different interference LTE scenarios by means of the Crámer-Rao bound (CRB) for time delay estimation, in order to assess the LTE positioning capabilities.

The Long Term Evolution (LTE) is a mobile communication standard that is receiving significant attention, and especially offers positioning capabilities by specifying a dedicated downlink signal, i.e. the positioning reference signal (PRS). Thus, this technology can improve the location of mobile terminals operating in harsh environments, such as urban or indoor scenarios. This paper presents a study of the impact of the channel on the positioning capabilities of LTE with respect to the signal bandwidth. For that purpose, typical channel models, such as those recommended by the International Telecommunication Union (ITU), are used to obtain timing error distributions by means of the histogram of maximum likelihood estimates. The results obtained represent the worst-case scenario since the applied estimation process does not consider the presence of the multipath channel. The dependency of the timing error distributions with respect to the type of channel model is also analysed.

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