A novel series of carbohydrate-based naphthoquinones was synthesized and evaluated for cytotoxicity against different human cancer cell lines (HCT-116, A-549 and MDA-MB 435). The compounds derived from juglone showed better cytotoxicity profiles.

In this work we described the synthesis and antimicrobial evaluation of 7-arylamino-5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates derivatives that exhibited remarkable activity against two Gram-negative strains of clinical importance.

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