Background: Diabetes mellitus (DM) is a serious metabolic disorder which causes blood glucose to rise in blood streams abnormally emanating from the difficulty in insulin secretion, its action or the two. The absence of effective modern treatments, the lifelong treatment with modern medicine their associated health side effects and their expensive prices etc. are among the challenging existing realities which devastate/worsen the health and economic burdens of the disease, especially in developing nations. In light of these, the search for cheaper, safe and potential drugs from medicinal plants is very crucial.
Background: Rabies is a deadly zoonotic viral disease. It is a major public-health problem which presents huge economic and health burdens in most parts of the developing world. The disease is difficult to treat once the clinical manifestations start to develop; the vaccines produced in mammalian neural tissues have the disadvantage of causing severe adverse reactions. This leads to the practice of traditional medicine for the control of rabies in most parts of Ethiopia for many years.
The genus Rumex is cosmopolitan plants consisted of about 200 species. Rumex nervosus that is known as nutraceutical plants widely distributed around the world. This review documents fragmented information on the ethnomedicial uses, phytochemistry and pharmacological activities of R. nervosus. The review articles are carried out by searching in PubMed, Google scholar and Google search up to December 2020. R. vernosus is traditionally used to treat eye disease, headache, teaniacapitis, haemorrhoids, dysentery, stomach-ache, diarrhoea, pharyngitis, arthritis, eczema, abscess and gynecological disorders. Secondary metabolites such as anthraquinones, naphthalenes, flavonoids, stilbenoids, triterpenes, carotenoids, and phenolic acids have been identified for this herb. The extracts of R. nervosus exhibited a wide range of pharmacological effects including antimicrobial, anti -inflammatory, antihypertensive, antidiabetic, antidiarrheal, anticoccidial and antileishimanial activities. These pharmacological studies have established a scientific basis for therapeutic uses of R. nervosus.
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