ABSTRACT. Vargeão Dome constitutes a rare example of a complex meteoritic impact structure formed in the Cretaceous volcanic lava flows of Serra Geral Formation, in South America. This conspicuous circular depression has its center at 26 • 49 S and 52 • 10 W and a diameter of 12.4 km. Impact deformation features found at Vargeão include shatter cones in sandstone and basalt, as well as planar deformational features in quartz. Available geophysical data for this structure comprise airborne magnetics and seismic surveys, which were processed and interpreted in combination with remote sensing data, such as digital elevation model generated by the SRTM (Shuttle Radar Topographic Mission) and Radarsat-1 and TERRA/ASTER satellites images. Magnetic and seismic data analysis allowed: (i) to interpret it as shallow structure, with a strongly deformed zone underneath; (ii) to associate a magnetic high spatially coincident with the central portion of the structure to the occurrence of pseudotachylite impact breccia; (iii) to associate the circular magnetic low located near the rim of the structure to the occurrence of large blocks of theÁcidas Chapecó volcanics unit. Favorable exposure of the shocked rocks, combined with easy access, makes this impact structure potentially important for conducting analogue studies of planetary surfaces, thus helping to understand the evolution of solid bodies such as the Moon, Mars, Venus, among others.Keywords: impact crater, shock metamorphism, volcanic lava flows, Serra Geral Formation. RESUMO. O Domo de Vargeão representa um notável e raro exemplo de estrutura de impacto meteorítico formada sobre derrames vulcânicos cretáceos da FormaçãoSerra Geral, na América do Sul. Esta conspícua depressão circular tem seu centro localizado em 26 • 49 S e 52 • 10 W, e possui 12,4 km de diâmetro. No interior do Domo ocorrem feições características de deformação por impacto, tais como shatter cones em arenitos e basaltos, e feições microscópicas do tipo deformação planar em quartzo. Dados magnéticos e sísmicos de reflexão disponíveis para a região da estrutura foram processados e interpretados em conjunto com dados de sensoriamento remoto, tais como modelos digitais de elevação SRTM (Shuttle Radar Topographic Mission ) e imagens Radarsat-1 e TERRA/ASTER. A análise dos dados magnéticos e sísmicos permitiu: (i) classificar o Domo de Vargeão como uma estrutura de expressão crustal rasa, com indicativos da existência de uma zona de intensa deformação situada abaixo da mesma; (ii) associar o alto magnético coincidente com o núcleo da estruturaà ocorrência de brechas de impacto do tipo pseudotaquilíticas; e (iii) associar a zona de baixo magnético, localizada próximaàs bordas da estrutura,à ocorrência de blocos da unidadeÁcidas Chapecó. O grau de exposição e fácil acesso aos afloramentos rochosos em seu interior tornam esta estrutura um sítio potencial para a realização de estudos de análogos em processos de evolução das superfícies planetárias, que contribuam para o entendimento da evolução de corpos plane...

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A prospective, multicenter study was carried out over a period of 10 months. All patients with clinically significant bacteremia caused by Enterococcus spp. were included. The epidemiological, microbiological, clinical, and prognostic features and the relationship of these features to the presence of high-level resistance to gentamicin (HLRG) were studied. Ninety-three patients with enterococcal bacteremia were included, and 31 of these cases were caused by HLRG (33%). The multivariate analysis selected chronic renal failure, intensive care unit stay, previous use of antimicrobial agents, andEnterococcus faecalis species as the independent risk factors that influenced the development of HLRG. The strains with HLRG showed lower levels of susceptibility to penicillin and ciprofloxacin. Clinical features (except for chronic renal failure) were similar in both groups of patients. HLRG did not influence the prognosis for patients with enterococcal bacteremia in terms of either the crude mortality rate (29% for patients with bacteremia caused by enterococci with HLRG and 28% for patients not infected with strains with HLRG) or the hospital stay after the acquisition of enterococcal bacteremia. Hemodynamic compromise, inappropriate antimicrobial therapy, and mechanical ventilation were revealed in the multivariate analysis to be the independent risk factors for mortality. Prolonged hospitalization was associated with the nosocomial acquisition of bacteremia and polymicrobial infections.

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Multimedia Interactive Informative Systems (MIIS) are software applications resulting from the convergence of multiples technologies such as audiovisual, computing and communication. They aim to transmit information to a large, diverse and dispersed public. As with other mass media, the fulfillment of MIIS goals depends largely on the quality of communication between the system and end users. Therefore, those systems should be developed in order to ensure that this quality requirement is satisfied. If MIIS are constructed according to usual software engineering practices, the analysis discipline of the development process includes requirements identification and specification; however, these techniques are focused on functional requirements, and they do not give much importance to non-functional requirements. In this paper, we propose a development process based on the production of videogames which has two different phases: preproduction and production. The first phase, corresponding to requirements identification, derives into the concept of system. In order to translate this concept into a specification, we propose the use of new communicational attributes and a MIIS metamodel. The establishment of MIIS non-functional specification is the result of analyzing class diagrams through quality attributes. In order to evaluate if the specifications are responding to communicational attributes, a functional prototype is built and evaluated with end users. The proposed methodology is applied to a real case study.