The frequency of accessory nipples in black Americans is almost eight times greater than in white European patients. Association of a wide range of abnormalities with supernumerary nipples in whites has, thus far, not been our experience in black Americans.
Not uncomonly, p a t i e n t s w i t h SCA e x h i b i t g a s t r o i n t e s t i n a l symptoms such a s c o n s t i p a t i o n , abdominal p a i n and a n o r e x i a . Moreover, t h e s e p a t i e n t s may a l s o grow poorly. I t i s p o s s i b l e t h a t poor growth and abnormal i n t e s t i n a l functions a r e c a u s a l l y r e l a t e d .
T h i s s t u d y was undertaken t o determine: 1 ) t h e p o s s i b l e r el a t i o n s h i p between t h e impaired growth and g a s t r o i n t e s t i n a l d i s o r d e r s ;2) t h e common g a s t r o i n t e s t i n a l abnormalities s e e n i n p a t i e n t s w i t h SCA; and 3) information on t h e s t a t u s of gast r o i n t e s t i n a l a b s o r p t i o n i n p a t i e n t s w i t h SCA.The adequacy of d i g e s t i o n , a b s o r p t i o n , m o t i l i t y and morphology of t h e g a s t r o i n t e s t i n a l t r a c t of c h i l d r e n with SCA was i n v e s t i g a t e d , u t i l i z i n g s e v e r a l t e s t s and procedures which included: Oral glucose t o l e r a n c e t e s t , Xylose a b s o r p t i o n f a t c o n t e n t i n 3 day pooled specimens of f e c e s , g e l a t i n a b s o r p t i o n I n a d d i t i o n , j e j u n a l b i o p s i e s were performed on t h r e e p a t i e n t s using t h e Robin's capsule technique. Electron-microscopic examination was performed on biopsy specimens.S i x t e e n p a t i e n t s w i t h homozygous s s anemia and two p a t i e n t s w i t h s i c k l e cell-hemoglobin C d i s e a s e and s i x t e e n matched nonanemic c h i l d r e n ( c o n t r o l s ) were s t u d i e d . Our i n v e s t i g a t i o n u s i n g t h e described techniques f a i l t o d i s c l o s e a n y s i g n i f i c a n t a b n o r m a l i t i e s of t h e g a s t r o i n t e s t i n a l t r a c t i n c h i l d r e n w i t h SCA.CORRECTION OF THE "PHYSIOLOGIC" MALABSORPTION OF THE PREMATURE B Y A MEDIUM CHAIN TRIGLYCERIDE(MCT) FORMULA. C.C. Roy, M. Ste-Marie, A. Weber, H. Bard and B. Doray, Univ.of Montreal, H s p i t a l S a i n t e -J u s t i n e , Dept. of P e d i a t r i c s .Low duodenal b i l e a c i d c o n c e n t r a t i o n s i s t h e main f a c t o r responsible f o r t h e f a t malabsorption of t h e newborn and t h e abs o r p t i o n of MCT i s l a r g e l y independent of m i c e l l a r s o l u b i l i s at i o n . One week a f t e r b i r t h , 2 i s o c a l o r i c formulas, of ident i c a l p r o t e i n ( c a s e i n h y d r o l y s a t e ) and carbohydrate (dextrose) c o n t e n t , d i f f e r i n g by t h e type of f a t (MCT vs Long Chain Triglycerides-LCT-) were f e d t o 25 preterm b a b i e s weighing 1300 t o 1800 g. During an i n i t i a l 1 5 day p e r i o d , each baby received e i t h e r MCT o r LCT, t h e a l t e r n a t e formula being given f o r t h e second feeding p e r i o d of i d e n t i c a l d u r a t i o n . On MCT, t h e r e was a drop i n s t o o l f a t (7.5+1.lg/72hr) and b i l e a c i d s 21.9+8.0mg/Kg/72hr a s w e l l a s a s i g n i f i c a n t i n c r e...
The recent extensive use of methadone for treatment of heroin addiction has taught that, in adults, withdrawal of methadone can produce a withdrawal syndrome similar to heroin. After considerable experience with heroin withdrawal in neonates and in view of controversy and limited studies regarding methadone withdrawal, the study herein reported was undertaken to compare the experiences with both heroin and methadone withdrawal symptoms in newborns. A number of methadone-treated pregnant women deliver their infants at Freedmen's Hospital, affording the opportunity to observe neonates born to methadone-addicted mothers.
The c l i n i c a l course of 55 back-transported (BT) i n f a n t s was com~ared with t h a t of 49 i n f a n t s who remained a t a reqional ~e r i natal center f o r convalescent care (NT). Although the-mean b i r t hweight and mean gestational age of the BT i n f a n t s was s i g n i f ic a n t l y l e s s than t h a t of N T i n f a n t s (BT = 1614+522 gms and 32t2.7 wks, N T = 1902+626 and 33.112.5; p <0.
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