Background & Aims: Microlithiasis is a common increasing disorder, especially in infants and young children, defined as sonographic detection of hyperechogenic deposits in the pelvic area of the ureter and calyces which are less than 3 mm in diameter. Potassium citrate is one of the drugs used in nephrolithiasis. Citrate prevents the formation of calcium deposits. It also inhibits calcium oxalate crystals, which can be the nidus for kidney stones. The aim of this study was to compare the effect of potassium polycitrate versus no treatment in the infants with microlithiasis. Materials & Methods:In this descriptive-retrospective study, 112 patients referred to a pediatric nephrology clinic were enrolled.Children less than two years old with microlithiasis in kidneys or urinary tract confirmed by ultrasonography imaging were included in the study. Patients were randomly divided into two groups: the first group received potassium citrate solution of 1-2 mEq/kg of body weight daily for two months, and the second group did not receive any specific medication. Follow-up was performed every two months for six months using ultrasound by a skilled radiologist with a fixed ultrasound device. To minimize drug side effects and treatment response, the allergic responses were measured once every two months, and the physician decided drug will or will not continue. Data analysis was done by SPSS 19. The P values <0.05 were considered significant. Results:The mean age of the study population was 4.13 ± 2.27 months. The mean weight in the total study population was 6.62±1.36 kg and the mean birth weight in the total study population was 3±0.41 kg. According to the results of the study, the decrease in the size or number of stones in one or both kidneys was more in the recipients of polycitrate solution and the increase in the size or number of stones in one or both kidneys was more in the infants not receiving polycitrate (P<0.001).Conclusions: Factors such as age, sex, current weight, birth weight and type of nutrition have no effect on improving and/or reducing the size and number of renal stones. However, in the group receiving potassium polycitrate solution, there was a significant reduction in the size and number of stones compared to the non-receiving group.
Background & Aims Seizure is a chronic neurological disease and a disorder of the nervous system caused by severe and sudden electrical discharge of neural cells. Status epilepticus is defined as any generalized tonic-colonic seizures lasting more than 5 minutes, any focal seizures lasting more than 10 minutes, and recurrent seizures without returning to baseline between periods of seizures. This study was designed and conducted to investigate the demographic and clinical characteristics of children with status epilepticus admitted to Motahari Hospital in Urmia during 2011-2019. Materials & Methods: This is a descriptive-retrospective study. All the files having the following criteria were included in the study: having a full record of patients' data, all the paraclinical studies performed, having a final diagnosis of status epilepticus, and having the age less than 18 years. History of epilepsy in the patient and first-degree relatives, and the patient's demographic information were recorded in the checklist. Results:The results of this study showed that the mean age and birth weight of patients with status epilepticus in Urmia Shahid Motahari Hospital was 37.49 months and 3046.30 grams, respectively. About 47% of patients had a previous history of epilepsy, 28.3% of parents were relative, 18.3% had a family history of epilepsy, 51.1% had a positive history of neurological disorder, and 8.7% had a positive history of non-neurological disorder. Boys were affected more than girls. EEG abnormality was the most common abnormal paraclinical finding (32.9%). Most of the patients had fever (74.9%) and the majority of seizures were manifested as generalized ones (82.6%). The mortality rate among these patients was 12.3%. Conclusion:According to the results of the present study, the deceased patients were significantly younger than the discharged individuals. Males outnumbered females in our study.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.