A thermoresponsive, 3D hinged metal-organic framework (HMOF-1) assembled from meso-tetra(4-pyridyl)porphine and CdI(2) exhibits a 3D "lattice fence" topology with extraordinary thermal expansion and shrinkage. A simple structural model is established to elucidate such a drastic thermal response. The hinged structure model presented here can also be applied to other "lattice fence" topologies with little or no modification, depending on the symmetry of the molecular building blocks.