ABSTRACT. T h e m e t h o d s u s e d b y c o l l a b o r a t o r s i n t h e I n t e r n a t i o n a l S t r e p t o m y c e s P r o j e c t (ISP)f o r . e m e n d a t i o n of d e s c r i p t i o n s of t y p e a n d n e o t y p e s t r a i n s of t h e g e n u s S t r e p t o m y c e s ( A c t i n o m y c e t a l e s ) a r e p r e s e n t e d . -------------An international cooperative effort, now i n progress, is directed toward collection of type cultures of the Streptomyces species for deposition with the Centraalbureau voor Schimmelcultures (CBS), Baarn. F r o m this center the reference cultures will be supplied to other culture collections s o that they a r e available throughout the world.An essential adjunct t o this activity is the redescription of each type culture in t e r m s of currently acceptable c r it e r i a and methods. Theurgent need for an authentic reference collection, accompanied by standardized characterizations f o r each species, has been pointed out by spokesmen f o r the several meetings and conferences which culminated i n this project.(See, for example, Gottlieb, 1959Gottlieb, , 1961 Kiister, 1959; Krasil'nikov, I961 .) More than 40 investigatorst representing 17 countries a r e participating in this research. Each culture is described independently by three of these cooperating specialists i n different laboratories before i t is deposited in the reference collection.This project is supported in part by a r e s e a r c h grant f r o m the National Science Foundation, U. S. A. The Subcommittee on Actinomycetes of the Committee on Taxonomy, A. S. M. and the Subcommittee on,Taxonomy of Actinomycetes of the International Committee on Bacteriological Nomenclature a r e co-sponsoring advisors.Participants in the 1964-1965 studies a r e listed on p. 338.

This is the final major publication of a series describing the type or suggested neotype strains for a total of more than 450 species of actinomycetes. Type strains or suggested neotype strains for species previously placed in the genera Streptomyces, Actinomyces sensu Krasil'nikov, or Streptoverticillium have been obtained from original authors, culture collections, or other reliable sources for redescription by currently acceptable criteria and methods. More than 40 collaborating laboratories representing 18 nations have cooperated in establishing methods and criteria, in locating authentic type strains, and especially in laboratory studies required for the emendations to descriptions. Specimens of the redescribed type strains or

ABSTRACT. T h e I n t e r n a t i o n a l S t r e p t o m y c e s P r o j e c t i s a c o o p e r a t i v e e f f o r t b y m o r e t h a n 4 0 c o l l a b o r a t i n g l a b or a t o r i e s r e p r e s e n t i n g 1 8 n a t i o n s t o a s s e m b l e a n d r ed e s c r i b e a u t h e n t i c t y p e s t r a i n s o r a c c e p t a b l e n e o t y p e s t r a i n s f o r s p e c i e s o f t h e g e n e r a S t r e p t o m y c e s a n d S t r e p t o v e r t i c i l l i u m . D e s c r i p t i o n s b a s e d u p o n c u r r e n tl y a c c e p t a b l e c r i t e r i a a n d m e t h o d s a r e p u b l i s h e d i n t h e I n t e r n a t i o n a l J o u r n a l o f S y s t e m a t i c B a c t e r i o l o g y . S p ec i m e n s o f t h e r e d e s c r i b e d t y p e s t r a i n s a r e d e p o s i t e d i n t h eA m e r i c a n T y p e C u l t u r e C o l l e c t i o n , t h e C e n t r a a lb u r e a u v o o r S c h i m m e l c u l t u r e s , t h e U . S . S . R . R e s e a r c h I n s t i t u t e f o r A n t i b i o t i c s a n d t h e I n s t i t u t e f o r F e r m e nt a t i o n , J a p a n . T h i s r e p o r t a d d s d e s c r i p t i o n s f o r t y p e s t r a i n s o f 1 0 0 a d d i t i o n a l s p e c i e s t o t h e 2 0 0 s p e c i e s p r e v i o u s l y d e p o s i t e d i n t h e c o l l e c t i o n s a n d d e s c r i b e d i n P a r t s I1 a n d I 1 1 of t h i s s e r i e s .-_ -_ ----_ _ -- --: $ A l e t t e r -n u m b e r combination i s assigned to each collaborating group. To conserve space, this code i s used to indicate the author group for each emended description. The l e t t e r A indicates collaborating groups for the f i r s t 130 type s t r a i n s distributed for study; B designates groups participating in the second study, etc. of Tokyo, Bunkyo-ku, Tokyo, Japan.F r a n k f u r t a / M -Hbchst, Germany. S Y S T E M A T I C B A C T E R I O L O G Y 39 3Baldacci, E. , G. F a r i n a and R. Recife, Pernambuco, Brazil. Group C-7Wallhaiis s e r , K a r l H. Mikrobiolog. Unter s, F a r b w e r k e Hoechst AG, Higgens, Calvin E. and R. E. Kastner. E l i Lilly and Co. , Indianapolis, WGznicka, Wanda. Pgnstwowy Higieny, U1. Chocimska 24, Warszawa 12, F r a n k f u r t a / M -Hochst, Germany.Indiana, U. S. A.Poland.Group C-8 Nakazawa, K . , M. Shibata, K. Yamamoto, E. Higashide, T. Iwasa and T. Hasegawa. Takeda Chem. Ind. , Ltd., Juso-Higashiyodogawaku, Osaka, Japan. Trejo, Wm. E. R. Squibb and Sons, New Brunswick, New J e r s e y , U. S. A. Routien, John B. and Corinne Clevenger. C h a r l e s P f i z e r and Co., Inc.Groton, Connecticut, U. S. A. a d d r e s s : B r i t i s h A m e r i c a n Tobacco Co., Ltd., Regents P a r k Rd.,