IntroductionPulmonary rehabilitation (PR) is a multidisciplinary program of care for patients with chronic obstructive pulmonary disease (COPD) with the goal of improving the functional capacity and quality of life, as well as maintaining the clinical stability of COPD sufferers. However, not all patients are available for such a program despite discomfort with their condition. The aim of this study was to evaluate the effects of a home-based PR (HBPR) program on functional ability, quality of life, and respiratory muscle strength and endurance.Patients and methodsPatients with COPD according to the Global Initiative of Chronic Obstructive Lung Disease were randomized (double-blind) into two groups. One group performed a protocol at home with aerobic and muscle strength exercises and was called the intervention group; the other group received only instructions to perform breathing and stretching exercises, characterizing it as the control group (CG). We assessed the following variables at baseline and 2 months: exercise tolerance (incremental shuttle walk test and upper limb test), respiratory muscle (strength and endurance test), and health-related quality of life (Airways Questionnaire 20).ResultsThere were no significant changes after the intervention in either of the two groups in exercise tolerance and quality of life. However, the intervention group had improved respiratory endurance compared with the CG, while the CG presented a decrease in the load sustained by the respiratory muscles after the HBPR.ConclusionA program of HBPR with biweekly supervision (although not enough to provide significant improvements in physical capacity or quality of life) played an important role in maintaining the stability of the clinical features of patients with COPD; the patients had no worsening of symptoms during the intervention period according to the daily log.
Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by chronic airflow limitation that leads beyond the pulmonary changes to important systemic effects. COPD is characterized by pulmonary and systemic inflammation. However, increases in the levels of inflammatory cytokines in plasma are found even when the disease is stable. Pulmonary rehabilitation improves physical exercise capacity and quality of life and decreases dyspnea. The aim of this study was to evaluate whether a home-based pulmonary rehabilitation (HBPR) program improves exercise tolerance in COPD patients, as well as health-related quality of life and systemic inflammation. This prospective study was conducted at the Laboratory of Functional Respiratory Evaluation, Nove de Julho University, São Paulo, Brazil. After anamnesis, patients were subjected to evaluations of health-related quality of life and dyspnea, spirometry, respiratory muscle strength, upper limbs incremental test, incremental shuttle walk test, and blood test for quantification of systemic inflammatory markers (interleukin [IL]-6 and IL-8). At the end of the evaluations, patients received a booklet containing the physical exercises to be performed at home, three times per week for 8 consecutive weeks. Around 25 patients were enrolled, and 14 completed the pre- and post-HBPR ratings. There was a significant increase in the walked distance and the maximal inspiratory pressure, improvements on two components from the health-related quality-of-life questionnaire, and a decrease in plasma IL-8 levels after the intervention. The HBPR is an important and viable alternative to pulmonary rehabilitation for the treatment of patients with COPD; it improves exercise tolerance, inspiratory muscle strength, quality of life, and systemic inflammation in COPD patients.
Hence the exploration of RMS using more restricted age ranges could contribute to a greater elucidation of the predictive values for MIP and MEP in children. Thus the objective of this study was to develop predictive equations for the RMS in 5 to 10year old children. Methods Population studied This was a cross-sectional study in which 148 five to ten year old children of both sexes took part. The study was approved by the Ethics in Research Committee of the Nove de Julho University (UNINOVE), report n° 69799/2012. The respective legal representatives of the children evaluated read and signed a Free and Clarified Term of consent before the evaluations.
Introdução: A doença pulmonar obstrutiva crônica é caracterizada por limitação do fluxo aéreo, não totalmente reversível. Os pacientes frequentemente apresentam intolerância ao exercício, dispneia e pior qualidade de vida. Objetivo: Avaliar a correlação de variáveis espirométricas, capacidade funcional e índice i-BODE com a qualidade de vida em sujeitos com DPOC. Métodos: Realizou-se estudo transversal no Laboratório de Avaliação Funcional Respiratória da Uninove. Os 23 pacientes com DPOC realizaram as seguintes avaliações: anamnese, qualidade de vida e dispneia, espirometria, composição corporal e incremental shuttle walk test. Resultados: Encontrou-se correlação significativa entre o SF-36 e o AQ-20 com a função pulmonar, a distância percorrida e o i-BODE, e as variáveis que mais apresentaram contribuição associativa com a qualidade de vida foram IMC, massa gorda, VEF1, DP e índice i-BODE. Conclusões: Pacientes com DPOC com qualidade de vida mais prejudicada apresentam maior comprometimento da função pulmonar, menor capacidade de exercício e menor sobrevida.
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