Background With enough advanced notice, dengue outbreaks can be mitigated. As a climate-sensitive disease, environmental conditions and past patterns of dengue can be used to make predictions about future outbreak risk. These predictions improve public health planning and decision-making to ultimately reduce the burden of disease. Past approaches to dengue forecasting have used seasonal climate forecasts, but the predictive ability of a system using different lead times in a year-round prediction system has been seldom explored. Moreover, the transition from theoretical to operational systems integrated with disease control activities is rare. Methods and findings We introduce an operational seasonal dengue forecasting system for Vietnam where Earth observations, seasonal climate forecasts, and lagged dengue cases are used to drive a superensemble of probabilistic dengue models to predict dengue risk up to 6 months ahead. Bayesian spatiotemporal models were fit to 19 years (2002–2020) of dengue data at the province level across Vietnam. A superensemble of these models then makes probabilistic predictions of dengue incidence at various future time points aligned with key Vietnamese decision and planning deadlines. We demonstrate that the superensemble generates more accurate predictions of dengue incidence than the individual models it incorporates across a suite of time horizons and transmission settings. Using historical data, the superensemble made slightly more accurate predictions (continuous rank probability score [CRPS] = 66.8, 95% CI 60.6–148.0) than a baseline model which forecasts the same incidence rate every month (CRPS = 79.4, 95% CI 78.5–80.5) at lead times of 1 to 3 months, albeit with larger uncertainty. The outbreak detection capability of the superensemble was considerably larger (69%) than that of the baseline model (54.5%). Predictions were most accurate in southern Vietnam, an area that experiences semi-regular seasonal dengue transmission. The system also demonstrated added value across multiple areas compared to previous practice of not using a forecast. We use the system to make a prospective prediction for dengue incidence in Vietnam for the period May to October 2020. Prospective predictions made with the superensemble were slightly more accurate (CRPS = 110, 95% CI 102–575) than those made with the baseline model (CRPS = 125, 95% CI 120–168) but had larger uncertainty. Finally, we propose a framework for the evaluation of probabilistic predictions. Despite the demonstrated value of our forecasting system, the approach is limited by the consistency of the dengue case data, as well as the lack of publicly available, continuous, and long-term data sets on mosquito control efforts and serotype-specific case data. Conclusions This study shows that by combining detailed Earth observation data, seasonal climate forecasts, and state-of-the-art models, dengue outbreaks can be predicted across a broad range of settings, with enough lead time to meaningfully inform dengue control. While our system omits some important variables not currently available at a subnational scale, the majority of past outbreaks could be predicted up to 3 months ahead. Over the next 2 years, the system will be prospectively evaluated and, if successful, potentially extended to other areas and other climate-sensitive disease systems.
Interpretation of surface fault scarps and palaeoseismic trenches is a key component of estimating fault slip rates, earthquake recurrence rates and maximum magnitudes for hazard assessments. Often these analyses rely on the assumption that successive earthquakes all breached the surface and that the ruptures are recorded topographically, or by the deposits exposed in a trench. The M w 7.2 1992 Suusamyr earthquake, Kyrgyzstan, is an apparently problematic case for such analyses because its ruptures show significant displacement but are only mapped as having broken the surface along small, disparate portions of the fault. Here we present the results of surveys conducted along the Suusamyr Fault to establish whether that is the case. Two sets of ruptures were identified following the earthquake. They are unusually short for their displacement and are separated by a 25 km gap. Using satellite imagery, high-resolution digital elevation models and palaeoseismic trenching we first reassess the distribution of the 1992 2 E.A. Ainscoe et al.ruptures and then reconstruct the Holocene earthquake record to establish the extent to which the 1992 earthquake is representative of the rupture behaviour of this fault. We find evidence for at least two prehistoric surface rupturing earthquakes in the Holocene: one ∼3 ka and one >8 ka that, along with the modern event, gives recurrence intervals of ∼3 kyr and ∼5 kyr.Within spatial gaps between segments of the 1992 ruptures there are clear prehistoric surface ruptures and the ruptures in each prehistoric earthquake were discontinuous. We conclude that there is significant variability in the surface rupture pattern of successive earthquakes on the Suusamyr Fault, with implications for the completeness of palaeoseismic records obtained from thrust scarps.
The relationship between individual earthquakes and the longer‐term growth of topography and of geological structures is not fully understood, but is key to our ability to make use of topographic and geological data sets in the contexts of seismic hazard and wider‐scale tectonics. Here we investigate those relationships at an active fold‐and‐thrust belt in the southwest Tarim Basin, Central Asia. We use seismic waveforms and interferometric synthetic aperture radar (InSAR) to determine the fault parameters and slip distribution of the 2015 Mw6.3 Pishan earthquake—a blind, reverse‐faulting event dipping toward the Tibetan Plateau. Our earthquake mechanism and location correspond closely to a fault mapped independently by seismic reflection, indicating that the earthquake was on a preexisting ramp fault over a depth range of ∼9–13 km. However, the geometry of folding in the overlying fluvial terraces cannot be fully explained by repeated coseismic slip in events such as the 2015 earthquake nor by the early postseismic motion shown in our interferograms; a key role in growth of the topography must be played by other mechanisms. The earthquake occurred at the Tarim‐Tibet boundary, with the unusually low dip of 21°. We use our source models from Pishan and a 2012 event to argue that the Tarim Basin crust deforms only by brittle failure on faults whose effective coefficient of friction is ≤0.05 ± 0.025. In contrast, most of the Tibetan crust undergoes ductile deformation, with a viscosity of order 1020–1022 Pa s. This contrast in rheologies provides an explanation for the low dip of the earthquake fault plane.
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