a straightforward relationship between herpes zoster and inactivated COVID-19 vaccine, immune dysregulation created by the vaccine may play a role in the reactivation of latent VZV infection in the current case. COVID-19 pandemic seems to be a favorable period for large-scale epidemiological studies to elucidate the relationship between the vaccination and herpes zoster reactivation due to planned massive vaccination.
We report a case of reversible sensorineural hearing loss due to hydroxychloroquine (HQ) treatment. The patient was a 34-year-old woman with 1 year of rheumatoid arthritis (RA). She developed reversible hearing loss after 5 months of HQ treatment. Sensorineural deafness has previously been reported with chloroquine treatment, but this is the first report of ototoxicity associated with HQ in RA.
Wide range of cutaneous side effects are being reported with different types of SARS-CoV-2 vaccines including early-onset or delayedtype local injection reactions, maculopapular rash, erythema multiforme, pernio, and urticaria. 1 Exacerbation of chronic inflammatory skin disorders such as psoriasis has also been described recently. 2 Herein, we present two cases of plaque psoriasis that exacerbated after inactivated and mRNA COVID-19 vaccination.
We present the case of a young woman suffering from both ankylosing spondylitis and Behçet's disease, associated with a severe inflammatory arthritis. Although the HLA phenotype was positive for HLA-B27 and negative for HLA-B5, the clinical findings, especially the joint manifestations of Behçet's disease, seem to appear dominantly. The meaning of this rare combination was discussed with a review of the literature.
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