The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has brought many unique pathologies, such as coagulopathy, prompting a desperate need for effective management. COVID-19-associated coagulopathy (CAC) can cause various thromboembolic complications, especially in critically ill patients. The pathogenesis is likely due to endothelial injury, immobilization, and an increase in circulating prothrombotic factors. Data on treatment are limited, although prophylactic anticoagulation is advised in all hospitalized patients. Herein, we have comprehensively reviewed the current literature available on CAC and highlight the pathogenesis, clinical features, and management of CAC. Key Messages Venous thromboembolism (VTE) is common in COVID-19 patients, especially those in the intensive care unit. Prophylactic anticoagulation is recommended in all patients with COVID-19 unless contraindicated.

No abstract

Acute epibulbar infections are one of the most frequently diagnosed ophthalmologic infections. They are usually self-limiting but can lead to a viral preseptal cellulitis mimicking a severe bacterial infection. Early diagnosis is important to shorten the course of recovery. Preseptal cellulitis is a soft-tissue infection that develops secondary to trauma, coryza, or local skin inflammation. Infections are usually bacterial with hemophilus influenzae, staphylococci, and streptococci being the most common pathogens. 1,2 Although viruses are rarely implicated in the etiology, varicella is known to cause preseptal cellulitis via an eyelid infection without prior respiratory involvement. Rarely, adenovirus eye infections are complicated by bulbar cellulitis. Herein, we present a case of a young man with an adenovirus-associated preseptal cellulitis diagnosed by pooled meta-genomic testing and successfully treated with topical steroids.

No abstract

No abstract