ABSTRACT. Adequate and effective treatment of severe pneumonia is especially relevant in present situation. The most problematic issue is infusion therapy. The current evidence and guidelines recommend balanced crystalloid infusion for patients with severe pneumonia and sepsis. The composition of Rheosorbilact® provides significant benefits in patients with severe infections, including respiratory infections. According to the results of the randomized open blinded end-point RheoSTAT-CP0698 study, administration of Rheosorbilact® to patients with pneumonia (intravenous infusion at a dose of 200-400 ml/day for 3 days) effectively improves the clinical condition, reduces the manifestations of (multi-) organ failure and endogenous intoxication. Small-volume infusion therapy promotes rapid normalization of circulating blood volume, stabilization of hemodynamics, acid-base, electrolyte and gas composition of the blood, significantly improves saturation and reduces tachypnea. The positive effect of therapy on renal function and inflammation has also been established. This therapy had a favorable safety profile (e. g., it did not lead to fluid overload, pulmonary edema, pleural effusion or other serious side effects, and was not associated with a clinically significant increase in endogenous serum lactate level). The RheoSTAT-CP0698 study substantiates the feasibility of using Rheosorbilact® in the complex treatment of pneumonia.
Tóm tắt: Bài báo này trình bày kết quả điều tra thảm thực vật ở KBTTN Mường Nhé, các quần xã thực vật được mô tả trong 5 kiểu: Rừng kín thường xanh mưa ẩm nhiệt đới (chỉ gồm các phân kiểu thứ sinh nhân tác), Rừng thứ sinh nửa rụng lá hơi khô nhiệt đới; Rừng kín thường xanh mưa ẩm á nhiệt đới (gồm cả các phân kiểu thứ sinh nhân tác); Rừng kín thường xanh mưa ẩm á nhiệt đới hỗn giao cây lá kim và Rừng rụng lá hơi khô á nhiệt đới (chỉ gồm phân kiểu thứ sinh nhân tác) và các quần xã cây trồng. Kết quả nghiên cứu cho thấy hiện nay rừng kín chỉ có ở vành đai á nhiệt đới. Hai trạng rừng rụng lá và nửa rụng lá vào mùa đông đem lại sắc thái riêng cho Mường Nhé và Tây Bắc. Nếu được bảo vệ để tái sinh, phục hồi tự nhiên thì các kiểu rừng kín sẽ có nhiều hy vọng phục hồi và thảm thực vật của Mường Nhé sẽ đạt được trạng thái ổn định nhất, góp phần không nhỏ cho công tác bảo tồn đa dạng sinh học Từ khóa: Mường Nhé, rừng thường xanh, rừng nửa rụng lá, rừng rụng lá. đóng vai trò quan trọng trong việc bảo vệ nguồn nước sinh hoạt, canh tác cho các cộng đồng địa phương và phòng hộ đầu nguồn sông Đà. Để góp phần vào công tác bảo tồn đa dạng sinh học nói chung và bảo tồn và phát triển rừng nói riêng, việc nghiên cứu đa dạng thảm thực vật có ý nghĩa quan trọng cả về mặt lý luận và thực tiễn bởi chưa có những nghiên cứu toàn diện nào vấn đề này ở Mường Nhé ngoài các công trình nghiên cứu, điều tra tổng thể đa dạng sinh học, đa dạng thực vật ở Mường Nhé của Hill et al. (1997) Mở đầu
Solar energy has now been applied to provide energy in many different fields around the world. In Vietnam, many solar energy projects are being implemented. In this transdisciplinarity research, research team and local stakeholders participate in designing a solar application to power a fruit and vegetable refrigerator located at Cu lao Rua, Thanh Hoi commune, Tan Uyen Town, Binh Duong province, Vietnam for the poor worker living in the disadvantaged localities with difficulties due to the impact of the Covid-19 pandemic. This is considered a community development project with the use of renewable energy, contributing to environmental protection of the new rural commune.
This study was conducted to assess the resources of oil plants in Xuan Nha special-use forest, Son La province. The survey period was conducted from July 2018 to June 2021. The results showed that there were 317 species, 196 genera of 62 families belonging to Pinophyta and Magnoliophyta. In addition to the value for essential oils, many species had other values such as 256 medicinal species, 105 edible species, 66 timber species, 35 bonsai species, 20 wine additive species, 9 species used for animal feeds, 7 dye-containing species and 3 poisonous species. The spectrum of life forms of identified species included: SB = 63.41Ph + 11.99 Th + 11.04Cr + 7.57Hm + 5.99 Ch. We have identified 24 species of plants as being endangered in the Vietnam Red Book (2007), 12 species listed in the Governmental Decree and 10 species in the red list of IUCN (2021). These are species with a small number of individuals that need to have policies for conservation and development.
Background. Pneumonia is a widespread disease and an often cause of hospitalizations both in Vietnam and Georgia. The supportive treatment of pneumonias includes the respiratory support, the support of fluid and electrolyte balance, parenteral nutrition and some additional drugs (analgesics, corticosteroids, inotropes). Rheo-STAT study is an interventional open-label randomized controlled study of Reosorbilact (“Yuria-Pharm”) effectiveness in pneumonia treatment. The study was held in 7 countries (Ukraine, Moldova, Georgia, Vietnam, Kazakhstan, Kyrgyzstan, Uzbekistan). Objective. To assess Reosorbilact effectiveness in the elimination of the intoxication syndrome. Materials and methods. 628 adult patients with sepsis, peritonitis, pneumonias and burns took part in this study. The pneumonia subgroup included 150 people (62 % males, mean age – 41.3 years, 33 % had some concomitant diseases). Inclusion criteria were the following: age – 18-60 years, community-acquired pneumonia and antibiotic therapy, administered not later than after 48 hours after the disease beginning, at least IV class according to PSI/PORT index, the presence of informed consent, baseline level of SOFA points ≥2. The assessment according to the SOFA scale on the 3rd day of treatment in comparison to the baseline level was the primary endpoint. Secondary endpoints included the change of mean result according to other scales (APACHE II, SAPS II, MODS, PSI/PORT, CURB-65) and changes of biochemical, immunological and integral markers of endogenous intoxication. Results and discussion. Infusion therapy with the help of Reosorbilact (200-400 ml per day) led to the increase of circulating blood volume and to the decrease of total infusion volume without any risk of volume overload. Lactate – one of the Reosorbilact components – did not increase the endogenous lactate level, which testifies a high safety. Inclusion of Reosorbilact into the combined treatment in 3 days led to the body temperature decrease from 39.37 to 36.77 °С, heart rate decrease from 105.27 to 77.81 bpm, leucocytes amount – from 9.38 to 6.64×109/L. Blood oxygenation also increased at the 3rd day of treatment, and PSI/PORT index decreased from 101.47 to 49.07. Pulmonary edema or pleural effusion were not revealed in any patients. Conclusions. 1. Pneumonia is a widespread disease, which often requires hospitalization. 2. Infusion therapy with the help of Reosorbilact increases the circulating blood volume without a risk of volume overload. 3. Inclusion of Reosorbilact into the combined treatment of pneumonia in 3 days leads to the decrease of body temperature, heart rate, leucocyte amount and to the increase of blood oxigenation.
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