The objective of this study was to evaluate biological and phytochemical properties of the aqueous extract from the leaves of Miconia chamissois Naudin (AEMC). Phytochemical properties were assessed by analyzing the chromatographic profile and the polyphenol content of AEMC. Biological properties evaluation was conducted based on cytotoxicity assay and by evaluating the antioxidant, antimicrobial, and enzymatic inhibition activities. Results indicated the presence of phytochemicals in AEMC such as flavonoids and polyphenols, including rutin, isoquercitrin and vitexin derivatives. AEMC showed antioxidant activity, which may be attributed to the high polyphenolic content. Moreover, AEMC demonstrated in vitro enzyme inhibition activity against tyrosinase and alpha-amylase, as well as showed low cytotoxicity. On the other hand, AEMC exhibited weak antimicrobial activity against S. aureus and C. albicans. Thus, AEMC is a promising alternative in search of potential drugs for the treatment of diseases induced by oxidative stress and inflammation, conditions due to hyperpigmentation processes, such as melisma, as well as for diabetes.
The purpose of this systematic review was to identify the available literature on the essential oil from species of genus Cordia. This study followed the Preferred Reporting Items for Systematic Reviews. The search was conducted on four databases: LILACS, PubMed, Science Direct, and Scopus until June 5th, 2020, with no time or language restrictions. Sixty out of the 1,333 initially gathered studies fit the inclusion criteria after the selection process. Nine species of Cordiawere reported in the selected studies, out of which 79% of the evaluated studies reported essential oil from Cordia curassavica. The essential oil extraction methods identified were hydrodistillation and steam distillation. As for biological application, antimicrobial, anti-inflammatory, larvicidal and antioxidant activities were the most reported. The main compounds reported for essential oil were β-caryophyllene, α-humulene, α-pinene, bicyclogermacrene, and sabinene. The information reported in this systematic review can contribute scientifically to the recognition of the importance of the genus Cordia.
As abelhas produzem a própolis a partir de materiais balsâmicos coletados das plantas. Trata-se de um produto natural com diversas funções dentro da colmeia. Atualmente, a ciência já comprovou várias ações biológicas desse material, tal como antioxidante. Porém, ainda há desafios no que concerne a padronização de técnicas de coleta, preparo da amostra, análises, controle de qualidade, dentre outros, dificultando o uso da própolis pela indústria. Essa revisão investigou os possíveis fatores de heterogeneidade do potencial antioxidante da própolis, considerando todo o processo de obtenção, desde origem das colmeias até formas de extração da própolis de abelha Apis mellifera. A busca desta revisão foi realizada nas seguintes bases de dados e ferramentas de busca: SciELO, Google Acadêmico, PubMed, MEDLINE, Catálogo de Dissertações e Teses da CAPES, BVS, CRD, Embase, Science Direct, Scopus e Cochrane Library. Foram incluídas publicações em português, inglês e espanhol (2011 a 2021). Foram obtidos 173 trabalhos que comprovaram importante atividade antioxidante do extrato de própolis de A. melífera. Porém, os resultados numéricos de potencial antioxidante diferiram muito entre si. Os principais fatores de heterogeneidade encontrados nas metodologias foram: local e época de coleta (sazonalidade), raça da abelha, tipo de própolis ou sua fonte botânica, e preparo do extrato (solvente, tempo e metodologia de extração).
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