To the EditorBlood cells in circulation could be disturbed both qualitatively and quantitatively in psychiatric disorders. Previous studies have reported alterations in the number (1,2) and function (3) of blood cells in psychiatric disorders. Alterations might be related to different etiologies in different psychiatric disorders (1) and medications (4,5). After the reversal of these mechanisms by successful treatment with escitalopram, the platelet volumes were normalized in first episode, medication-naïve patients with major depressive disorder (6). In bipolar disorder, mood stabilizers seem to be the major reason for the changes in blood cells (4,5). In patients with psychotic spectrum disorders, the mean platelet volume (MPV) is increased, especially in patients on atypical antipsychotics (7).We have analyzed the blood cell counts of outpatients in our clinic between 1 January, 2012 and 31 December, 2014. Major depressive disorder (n = 338), bipolar disorder (n = 389), and psychotic spectrum disorders (n = 227) were the diagnostic groups examined in our analysis. The results of
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