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Mastitis, a disease complex of multiple etiologies, results into considerable financial losses to dairy industry worldwide. A cross sectional study was carried out between July 2013 to August 2013 in Asella town and its surrounding areas in order to cefotaxime, penicillin G, amoxicillin, ampicillin and vancomycin, which accounted 97.9%, 96.4%, 80.4%, 80.2% and 78%, respectively. Staphylococcus aureus revealed resistance against penicillin G, amoxacillin and tetracycline, which accounted 97.9%, 96.4% and 80.4%, respectively and Escherichia coli showed resistance against vancomycin, ampicillin and penicillin G, which indicated 83%, 74% and 65%, respectively

No abstract