This case report outlines a novel conservative surgical approach to the management of a unicystic ameloblastoma with the use of marsupialisation, enucleation, cryotherapy and orthodontic extrusion to enable successful treatment without neurological damage or deformity. It has been increasingly recognized that conservative treatment of unicystic ameloblastomas, instead of wide local excision, can reduce morbidity whilst maintaining an acceptably low recurrence rate. Several case series have also demonstrated orthodontic extrusion of impacted third molars in moving the apex of the roots away from the inferior alveolar nerve. This is possibly the first case report of the combination of these two procedures in an adult with a large unicystic ameloblastoma. CPD/Clinical Relevance: This is not an infrequently seen neoplasia: this paper therefore has the opportunity to inform management of this condition amongst clinicians.
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