The specific immobilisation of a histidine-tagged protein, Spi, onto mono-anchored nickel(II)-cyclam functionalised SBA-15 is reported.Scheme 1 Surface modification of SBA-15 with Ni-cyclam and subsequent attachment of a His 6 -tagged protein.
Mesoporous silicates (MPS) possess ordered pore structures with pore diameters sufficiently large to accommodate a range of enzymes. The successful immobilization of an enzyme on MPS usually requires modification of the surface of MPS to optimize the interactions between the support and the enzyme. Recent developments on the 2 functionalization of MPS for the immobilization of enzymes are described in this review.
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