Mental fatigue impairs technical but not physical performance in small-sided soccer games.

The aim of this study was to assess elite women's basketball game performance. Five elite women's games (3 Italian first division and 2 Euroleague) were analyzed for individual and team time-motion analyses. The individual analysis evaluated the players' movement patterns with particular focus on high-intensity activity (HIA), sprint activity, and repeated sprint events (RSEs). Team analysis included live time (LT), stoppage time (ST), and their ratio, transfer (TR) phases, and half court and full court actions. The frequency of occurrence of changes of activities was n = 576 ± 110, one every 2.56 seconds of LT. Total HIA was 8.5 ± 1.8% of LT and no significant differences between quarter periods were observed. In general, players performed linear sprints (48.3 ± 2.9%) over 1-5 m distance (56.8 ± 5.6%). The occurrence of RSE was 4.4 ± 1.7, with 58.6 ± 18.5% passive recovery between sprints. Team analysis showed no significant difference between games for LT and ST phases (ratio = 1.18 ± 0.25). For game analysis, LT and ST were 43.4 ± 7.8% and 51.1 ± 8.4%, respectively. A difference between games was found for half court actions (p < 0.01) and TR phases (p ≤ 0.05). Moreover, 1 TR and 2 TR were the most performed (45.3 and 23.9%) actions. These results encourage coaches to include repeated sprint ability with mainly linear and short sprints into a comprehensive training program.

This study aimed to analyse the effects of two factors (number of players and training regimes) on players' physiological and technical demands in basketball ball-drills. Twenty-one young basketball players performed four different ball-drills (two levels for each factor). The number of players involved was 2vs2 and 4vs4, while ball-drill regimes were continuous and intermittent. Physiological demand was assessed using the percentage of maximal heart rate (%HRmax), Edwards' training load and rating of perceived exertion (RPE). Furthermore, the following technical actions were collected: dribbles, steals, rebounds, turnovers, passes (total, correct, wrong and % of correct pass) and shots (total, scored, missed and % of made shot). A 2 × 2 (number of players × regime) two-way ANOVA with repeated measures was applied for physiological parameters and technical actions. The 2vs2 condition showed higher %HRmax (P < 0.001), Edwards' training load (P < 0.001), RPE (P < 0.001), number of dribbles (P < 0.001), rebounds (P < 0.001), passes [total (P = 0.005) and correct (P = 0.005)] and shots [total (P < 0.001) scored (P < 0.001) and missed (P < 0.001)] than 4vs4. Moreover, the continuous regime revealed higher %HRmax (P < 0.001), Edwards' training load (P < 0.001), RPE (P = 0.006) and dribbles (P < 0.001) than the intermittent regime. This study showed that both number of players and regime are useful variables able to modify basketball ball-drills workload.

These findings provide college basketball coaches information to optimize training strategies during the in-season phase. Basketball coaches should concurrently consider the number of weekly games and player status (starting vs bench player) when creating individualized periodization plans, with increases in TL potentially needed in bench players, especially in 2-game weeks.

Acute primary open angle glaucoma is an optic neuropathy characterized by the elevation of intraocular pressure, which causes retinal ischemia and neuronal death. Rat ischemia/reperfusion enhances endocytosis of both horseradish peroxidase (HRP) or fluorescent dextran into ganglion cell layer (GCL) neurons 24 h after the insult. We investigated the activation of autophagy in GCL-neurons following ischemia/reperfusion, using acid phosphatase (AP) histochemistry and immunofluorescence against LC3 and LAMP1. Retinal I/R lead to the appearance of AP-positive granules and LAMP1-positive vesicles 12 and 24 h after the insult, and LC3 labelling at 24 h, and induced a consistent retinal neuron death. At 48 h the retina was negative for autophagic markers. In addition, Western Blot analysis revealed an increase of LC3 levels after damage: the increase in the conjugated, LC3-II isoform is suggestive of autophagic activity. Inhibition of autophagy by 3-methyladenine partially prevented death of neurons and reduces apoptotic markers, 24 h post-lesion. The number of neurons in the GCL decreased significantly following I/R (I/R 12.21±1.13 vs controls 19.23±1.12 cells/500 µm); this decrease was partially prevented by 3-methyladenine (17.08±1.42 cells/500 µm), which potently inhibits maturation of autophagosomes. Treatment also prevented the increase in glial fibrillary acid protein immunoreactivity elicited by I/R. Therefore, targeting autophagy could represent a novel and promising treatment for glaucoma and retinal ischemia.