In Brazil, Asian rust is the main disease that affects the soybean crop, which is responsible for the great inventiveness of financial resources with fungicides to control this pathogen. The objective of this work was to evaluate the grain yield and economic viability of the different combinations of fungicides used in the soybean crop. The experiment was conducted in the 2014/2015 agricultural year in the experimental field located in the municipality of Campo Novo-RS, Brazil. The treatments used correspond to 15 combinations of fungicides, and these were applied at different times during the soybean cycle. The characters measured weremass of 1000 seeds, grain yield, gross income, fungicide cost, total cost, net income, income gain and profitability. The grain yield of soybeans was reduced by 35% due to the absence of fungicide applications. Combinations of fungicides that provide the highest yields and profitability for soybean are based on the use of different active principles such asstrobilurins and carboxamides.
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