Introduction:Acute coronary syndrome (ACS) caused by coronary atherosclerosis include ST-segment elevation myocardial infarction (STEMI), non-STEMI, and unstable angina. The relation between psychiatric disorders and coronary artery disease is a complex one which includes the effect of the psychosocial factors on heart and vice versa. Point prevalence studies have been reported, but there is paucity of follow-up studies from India.Materials and Methods:The study is a follow-up evaluation at discharge of 248 consecutive patients presented with ACS at JSS Hospital, Mysuru, Karnataka, over a period of 6 months to assess the psychiatric comorbidities. The patients were assessed on a structured and validated pro forma before discharge, at 3 months, and at 6 months. Screening of psychiatric disorders was done using Mini International Neuropsychiatric Interview PLUS 5.0.0 and assessment of depression was done using Hamilton Depression Rating Scale. ANOVA, Student's t-test, and SPSS 21 were used for statistical analysis.Results:The most common psychiatric comorbidities include major depressive disorder (44%), it persisted at the end of 3 (P < 0.001) and 6 (P < 0.001) months. A spectrum of anxiety disorders including panic disorder (12.10%), dysthymia (3.60%), agoraphobia (2.40%), social phobia (2%), obsessive-compulsive disorder (1.6%), specific phobia (1.2%), and posttraumatic stress disorder (0.8%) in descending order at the end of 6 months were found. Significant reduction in substance use of nicotine (66.1%) and alcohol (56.0%) was reported on follow-up.Conclusion:Depression, anxiety, and substance use occur in patients with ACS which persist on follow-up. Early recognition at discharge and appropriate counseling on follow-up improve the clinical outcomes.
Introduction: Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality worldwide. Patients with coronary artery disease (CAD) have more than twofold risk of sexual dysfunction compared with age-matched healthy persons. Coronary artery bypass graft (CABG) surgery benefits in CAD populations are well established. Erectile dysfunction (ED) in men and arousal difficulties in women are highly prevalent in CAD, yet it is frequently under-recognized and under-diagnosed in clinical practice. A further study on the relation between CABG and sexual functioning is not much explored, hence the need for the study. Materials and Method: It is a cross-sectional study conducted in JSS Hospital, Mysuru, Karnataka. A total of 54 consecutive patients who have undergone CABG were considered. Informed and written consent was taken. After stabilization and thorough checkup by the attending cardiologist, interview was conducted. The patients were assessed on a structured and validated pro forma, for males International Index for Erectile Function (IIEF) and for females Female Sexual Function Index (FSFI) were used. ANOVA and Student’s t test, statistical software SAS 9.2, SPSS 15.0, Stata 10.1, MedCalc 9.0.1, Systat 12.0, and R environment ver.2.11.1 were used for statistical analysis. Results: Of the 54 study subjects, in males, 69.4% had mild to moderate ED, 52.8% had mild orgasmic dysfunction, 44.4% had moderate desire dysfunction, 50% had mild to moderate dysfunction of intercourse satisfaction, and 44.4% had mild to moderate and moderate dysfunction in overall satisfaction. In females, one or the other forms of sexual dysfunction were present in all the female study subjects; among them, 66.7% had arousal difficulties, 44.4% had lubrication, orgasm, and satisfaction problems and pain difficulties. Conclusion: The results obtained in this study showed an increased prevalence rate of sexual dysfunction in patients who have undergone CABG. Hence addressing the concerned issues during the stay in the hospital is necessary for the better outcomes.
Insulinoma is a functional endocrine tumor of the pancreas that secretes insulin. Insulinoma comprises 25% of the pancreatic endocrine tumors. Patients may have heterogeneous presentation of symptoms varying from mild autonomic symptoms to severe hypoglycemic episodes. Sometimes, insulinoma may present with neuropsychiatric symptoms which can be mistaken for seizure disorder or dissociative disorder. Careful evaluation of the patient with such symptoms is advised to avoid delay in diagnosis of Insulinoma. Here, we are reporting a case who presented with episodic confusional state of 7 years' duration that was misdiagnosed as refractory seizures. On further evaluation and monitoring, he was diagnosed with insulinoma, the details of which are elaborated in this case report.
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